2. Neuronal Signaling
  3. Cholinesterase (ChE)
  4. Bisnorcymserine

Bisnorcymserine  (Synonyms: N1,N8-Bisnorcymserine; (-)-Bisnorcymserine)

目录号: HY-121191
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摩尔计算器

Bisnorcymserine ((-)-Bisnorcymserine) 是丁酰胆碱酯酶 (BChE) 的抑制剂，IC50 为 0.228 nM。Bisnorcymserine 可降低淀粉样蛋白-β 肽 (Aβ) 的水平，改善老年大鼠模型中的阿尔茨海默病。Bisnorcymserine 具有血脑屏障通透性。

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Bisnorcymserine Chemical Structure

Bisnorcymserine Chemical Structure

CAS No. : 219920-81-7

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Bisnorcymserine 相关抗体

Top Publications Citing Use of Products

查看 Cholinesterase (ChE) 亚型特异性产品:

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AChE BChE

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Bisnorcymserine ((-)-Bisnorcymserine) is an inhibitor for butyrylcholinesterase (BChE) with an IC50 of 0.228 nM. Bisnorcymserine reduces the levels of amyloid-β peptide (Aβ), exhibits ameliorates the Alzheimer’s Disease in elderly rat models. Bisnorcymserine is blood-brain barrier penetrate[1].

IC50 & Target

BChE

0.228 nM (IC50)

分子量

351.44

Formula

C21H25N3O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Bisnorcymserine 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bisnorcymserine219920-81-7N1,N8-Bisnorcymserine (-)-BisnorcymserineCholinesterase (ChE)Alzheimer’s DiseaseBBB penetrateInhibitorinhibitorinhibit

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