2. Membrane Transporter/Ion Channel
  3. SGLT
  4. Canagliflozin-d6

Canagliflozin-d6  (Synonyms: JNJ 28431754-d6)

目录号: HY-10451S2
产品使用指南

摩尔计算器

Canagliflozin-d6 是 Canagliflozin 的氘代物。 Canagliflozin (JNJ 28431754) 是一种选择性的 SGLT2 抑制剂，作用于表达 mSGLT2，rSGLT2 和 hSGLT2 的 CHO细胞，IC50 分别为 2 nM，3.7 nM 和 4.4 nM。

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Canagliflozin-d<sub>6</sub> Chemical Structure

Canagliflozin-d6 Chemical Structure

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规格 是否有货
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Other Forms of Canagliflozin-d6:

Canagliflozin-d6 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Canagliflozin-d6 is the deuterium labeled Canagliflozin[1]. Canagliflozin (JNJ 28431754) is a selective SGLT2 inhibitor with IC50s of 2 nM, 3.7 nM, and 4.4 nM for mSGLT2, rSGLT2, and hSGLT2 in CHOK cells, respectively[2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Canagliflozin-d6 相关抗体:
分子量

450.55

Formula

C24H19D6FO5S
非标记 CAS
中文名称

卡格列净-d6；坎格列净-d6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Canagliflozin-d6 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Canagliflozin-d6JNJ 28431754-d6卡格列净-d6坎格列净-d6SGLTSodium-dependent glucose cotransportersInhibitorinhibitorinhibit

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目录号：
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