2. Cell Cycle/DNA Damage
  3. CDK
  4. CDK4 degrader 1

CDK4 degrader 1 (ML 1–71) 是一种靶向 CDK4 的单价降解剂。

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CDK4 degrader 1 Chemical Structure

CDK4 degrader 1 Chemical Structure

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CDK4 degrader 1 相关抗体

Top Publications Citing Use of Products

查看 CDK 亚型特异性产品:

查看所有亚型
CDK1 CDK2 CDK3 CDK4 CDK5 CDK6 CDK7 CDK8 CDK9 CDK11 CDK12 CDK13 CDK14 CDK16 CDK19 CDC CLK Pho85

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CDK4 degrader 1 (ML 1–71) is a monovalent degrader targeting CDK4[1].

IC50 & Target

CDK4

 

体外研究
(In Vitro)

CDK4 degrader 1 (0-10 μM; 24 h) 以剂量依赖性方式显著降解细胞中的 CDK4[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CDK4 degrader 1 相关抗体:

Western Blot Analysis[1]

Cell Line: C33A cervical cancer cells
Concentration: 0.1, 1, 5, 10 μM
Incubation Time: 24 h
Result: Significantly degraded CDK4 in cells in a dose-dependent manner.
分子量

524.64

Formula

C25H32N8O3S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CDK4 degrader 1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CDK4 degrader 1CDKCyclin dependent kinaseInhibitorinhibitorinhibit

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产品名称：
CDK4 degrader 1
目录号：
HY-163640
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