2. Cell Cycle/DNA Damage
  3. CDK
  4. CDK7-IN-7

CDK7-IN-7 是一种有效的 CDK7 抑制剂，IC50 为 <50 nM. 详细信息可参考专利 CN112661745A, compound T-01。

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CDK7-IN-7 Chemical Structure

CDK7-IN-7 Chemical Structure

CAS No. : 2640208-01-9

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CDK7-IN-7 相关抗体

Top Publications Citing Use of Products

查看 CDK 亚型特异性产品:

查看所有亚型
CDK1 CDK2 CDK3 CDK4 CDK5 CDK6 CDK7 CDK8 CDK9 CDK11 CDK12 CDK13 CDK14 CDK16 CDK19 CDC CLK Pho85

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CDK7-IN-7 is a potent and selective CDK7 kinase inhibitor with an IC50 of <50 nM (Patent CN112661745A, compound T-01)[1].

IC50 & Target[1]

CDK7

<50 nM (IC50)

体外研究
(In Vitro)

CDK7-IN-7 shows inhibitory against MDA‑MB 231, MDA-MB453, OVCAR3, A2780, HCT-116, WiDr and Calu-6 cells (IC50 ranging from 12.21 to 144.9 nM)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CDK7-IN-7 相关抗体:
分子量

513.31

Formula

C20H20BrF3N6O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CDK7-IN-7 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CDK7-IN-72640208-01-9CDKCyclin dependent kinasecyclindependentkinaseproliferativecancerMDA-MB 231MDA?MB453OVCAR3A2780HCT-116WiDrCalu-6 cellsInhibitorinhibitorinhibit

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目录号：
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