2. Immunology/Inflammation NF-κB
  3. COX NOD-like Receptor (NLR) NF-κB
  4. COX-2/NLRP3-IN-1

COX-2/NLRP3-IN-1 (Compound 6k) 是一种 COX-2/NLRP3 抑制剂，对 COX-2 的 IC50 为 1.53 μM。COX-2/NLRP3-IN-1 通过抑制 NF-κB/NLRP3 信号通路发挥抗炎作用。

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COX-2/NLRP3-IN-1 Chemical Structure

COX-2/NLRP3-IN-1 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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Customer Review

COX-2/NLRP3-IN-1 相关抗体

Top Publications Citing Use of Products

查看 COX 亚型特异性产品:

查看所有亚型
COX COX-1 COX-2 COX-3

查看 NOD-like Receptor (NLR) 亚型特异性产品:

查看所有亚型
NLRP3 NLRP1 NOD1 NOD2

查看 NF-κB 亚型特异性产品:

查看所有亚型
NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

COX-2/NLRP3-IN-1 (Compound 6k) is a COX-2/NLRP3 inhibitor with a IC50 of 1.53 μM for COX-2. COX-2/NLRP3-IN-1 exerts anti-inflammatory effects by inhibiting the NF-κB/NLRP3 signaling pathway[1].

IC50 & Target

COX-2

1.53 μM (IC50)

分子量

496.41

Formula

C24H19Cl2N5OS
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

COX-2/NLRP3-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

COX-2/NLRP3-IN-1COXNOD-like Receptor (NLR)NF-κBCyclooxygenaseNuclear factor-κBNuclear factor-kappaBCOX-2NLRP3InhibitorAnti-inflammatoryUlcerative colitisinhibitorinhibit

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产品名称：
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