1. PROTAC Protein Tyrosine Kinase/RTK
  2. Ligands for Target Protein for PROTAC FAK
  3. Defactinib analogue-1

Defactinib analogue-1 (Compound 7) 是靶蛋白 Fak 配体,可以用于合成 PROTAC FAK degrader 1 (HY-119932)。

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Defactinib analogue-1 Chemical Structure

Defactinib analogue-1 Chemical Structure

CAS No. : 2296719-34-9

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Defactinib analogue-1 (Compound 7) is a ligand for target protein Fak, that can be used for synthesis of PROTAC FAK degrader 1 (HY-119932)[1].

分子量

467.47

Formula

C20H20F3N5O3S

CAS 号
性状

固体

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

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参考文献
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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Defactinib analogue-1
目录号:
HY-44146
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