1. Neuronal Signaling
  2. Cholinesterase (ChE) Monoamine Oxidase
  3. Desoxypeganine hydrochloride

Desoxypeganine hydrochloride  (Synonyms: Deoxypeganine hydrochloride; Deoxyvasicine hydrochloride)

目录号: HY-108048A
产品使用指南

Desoxypeganine (Deoxypeganine) hydrochloride 是一种生物碱,是一种口服有效的胆碱酯酶 (BChEAChE) 和选择性 MAO-A 抑制剂,其 IC50 值分别为 2、17 和 2 μM。 Desoxypeganine hydrochloride 可用于酒精滥用研究。

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Desoxypeganine hydrochloride Chemical Structure

Desoxypeganine hydrochloride Chemical Structure

CAS No. : 61939-05-7

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规格 是否有货
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Other Forms of Desoxypeganine hydrochloride:

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Desoxypeganine (Deoxypeganine) hydrochloride, an alkaloid, is a potent and orally active cholinesterase (BChE and AChE) and selective MAO-A inhibitor, with IC50 values of 2, 17, and 2 μM, respectively. Desoxypeganine hydrochloride can be used for alcohol abuse research[1].

IC50 & Target

BChE

2 μM (IC50)

AChE

17 μM (IC50)

MAO-A

2 μM (IC50)

体内研究
(In Vivo)

Desoxypeganine hydrochloride (10-30 mg/kg,灌胃,每天一次,连续 16 天) 剂量依赖性地降低乙醇摄入量和乙醇偏好[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female Alko alcohol (AA) rats (Thirty eight adult)[1]
Dosage: 10, 20, 30 mg/kg
Administration: Gavage, once daily in a volume of 10 ml/kg at 6:00 pm, for 16 days
Result: Abolished ethanol preference.
分子量

208.69

Formula

C11H13ClN2

CAS 号
中文名称

去氧鸭嘴花碱盐酸盐

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Desoxypeganine hydrochloride
目录号:
HY-108048A
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