1. Neuronal Signaling
  2. Cholinesterase (ChE)
  3. Diphenyl diselenide

Diphenyl diselenide  (Synonyms: 二苯基二硒醚; 1,2-Diphenyldiselane; DPDSe)

目录号: HY-Z0942
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Diphenyl diselenide (1,2-Diphenyldiselane) 是一种有机硒化合物,是一种乙酰胆碱酯酶 (AChE) 抑制剂。Diphenyl diselenide 具有神经保护作用。

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Diphenyl diselenide Chemical Structure

Diphenyl diselenide Chemical Structure

CAS No. : 1666-13-3

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查看 Cholinesterase (ChE) 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Diphenyl diselenide (1,2-Diphenyldiselane), a organoselenium compound, is an acetylcholinesterase (AChE) inhibitor. Diphenyl diselenide has neuroprotective effects[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
786-0 IC50
38 μM
Compound: 2
Cytotoxicity against human 786-O cells after 48 hrs by MTT assay
Cytotoxicity against human 786-O cells after 48 hrs by MTT assay
[PMID: 24961641]
HL-60 IC50
32 μM
Compound: 2
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
[PMID: 24961641]
HT-29 IC50
31 μM
Compound: 2
Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay
Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay
[PMID: 24961641]
OVCAR-5 IC50
38 μM
Compound: 2
Cytotoxicity against human OVCAR5 cells after 48 hrs by MTT assay
Cytotoxicity against human OVCAR5 cells after 48 hrs by MTT assay
[PMID: 24961641]
PC-3 IC50
42 μM
Compound: 2
Cytotoxicity against human PC3 cells after 48 hrs by MTT assay
Cytotoxicity against human PC3 cells after 48 hrs by MTT assay
[PMID: 24961641]
SH-SY5Y IC50
30 μM
Compound: 29a
Antitumor activity against human SH-SY5Y cells assessed as induction of apoptosis by propidium iodide staining based flow cytometry analysis
Antitumor activity against human SH-SY5Y cells assessed as induction of apoptosis by propidium iodide staining based flow cytometry analysis
[PMID: 34217061]
分子量

312.13

Formula

C12H10Se2

CAS 号
中文名称

二苯基二硒醚

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Diphenyl diselenide
目录号:
HY-Z0942
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