2. Antibody-drug Conjugate/ADC Related Anti-infection Cell Cycle/DNA Damage Epigenetics PI3K/Akt/mTOR Apoptosis Autophagy
  3. ADC Cytotoxin Antibiotic Bacterial Topoisomerase AMPK HIV HBV Apoptosis Autophagy Mitophagy
  4. Dox-btn2

Dox-btn2 是 Doxorubicin (HY-15142A) 的生物素化衍生物，在 3'-NH2 与阿霉素的偶联点上有生物素标记。Dox-btn2 可用于细胞成像。Doxorubicin 主要积累在细胞核中，而 Dox-btn2 主要位于细胞质中。

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Dox-btn2 Chemical Structure

Dox-btn2 Chemical Structure

CAS No. : 3026061-31-1

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规格 价格 是否有货 数量
1 mg ￥9500
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Dox-btn2 相关抗体

Top Publications Citing Use of Products

查看 ADC Cytotoxin 亚型特异性产品:

查看所有亚型
Auristatin Calicheamicins Camptothecins Daunorubicins/Doxorubicins Duocarmycins Maytansinoids Pyrrolobenzodiazepines Traditional Cytotoxic Agents

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Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

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Topoisomerase Topo I Topo II

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NUAK1 NUAK2 AMPK AMPK α1β1γ1 AMPK α2β1γ1 AMPK α1β2γ1 AMPK α2β2γ1

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HIV HIV-1 HIV-2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Dox-btn2 is a biotinylated derivative of Doxorubicin (HY-15142A), with a biotin label at the point of conjugation to doxorubicin at 3'-NH2. Dox-btn2 can be used for cell imaging. While Doxorubicin is mainly accumulated in the nucleus, while Dox-btn2 is mainly located in the cytoplasm[1].

体外研究
(In Vitro)

Dox-btn2 (1 μM；6 h；Exc=531/40 nm，Emi=593/40 nm) 在 U2OS 细胞中显示可视化，帮助绘制定位与 DNA 和染色质蛋白相互作用的原位图谱[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Dox-btn2 相关抗体:
分子量

1017.10

Formula

C48H64N4O18S
CAS 号
性状

固体

颜色

Brown to orange

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

纯度 & 产品资料
参考文献

Dox-btn2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dox-btn23026061-31-1ADC CytotoxinAntibioticBacterialTopoisomeraseAMPKHIVHBVApoptosisAutophagyMitophagyADC PayloadAMP-activated protein kinaseHuman immunodeficiency virusHepatitis B virusMitochondrial Autophagy3'-NH2cell imagingnucleuscytoplasmvisualizationInhibitorinhibitorinhibit

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目录号：
HY-153797
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