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Echothiopate chloride  (Synonyms: Echothiophate chloride)

目录号: HY-16183A
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Echothiophate (Echothiophate) chloride 是一种高效、长效的胆碱酯酶抑制剂，可用作抑制青光眼的缩瞳剂。Echothiopate chloride 通过其磷酸基与胆碱酯酶活性位点的丝氨酸残基形成共价键，使酶永久失活，并需要细胞合成新的酶。由于其与胆碱酯酶的不可逆结合和极慢的水解速度，埃可托菲特的效果可以持续一周或更长时间。Echothiopate chloride 被用作眼部抗高血压药，用于抑制慢性青光眼，在某些情况下还用于抑制调节性内斜视。

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Echothiopate chloride Chemical Structure

Echothiopate chloride Chemical Structure

CAS No. : 120087-68-5

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Other Forms of Echothiopate chloride:

Echothiopate chloride 相关抗体

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生物活性

Echothiophate (Echothiophate) chloride is a highly effective, long-lasting cholinesterase inhibitor employed as a miotic for managing glaucoma. Echothiopate chloride forms a covalent bond with the serine residue at the active site of cholinesterase through its phosphate group, rendering the enzyme permanently inactive and necessitating the synthesis of new enzymes by the cell. Given its irreversible binding to cholinesterase and the extremely slow rate of hydrolysis, the effects of echothiophate can persist for a week or longer. Echothiopate chloride is utilized as an ocular antihypertensive agent in the treatment of chronic glaucoma and, in certain cases, accommodative esotropia.

分子量

291.78

Formula

C9H23ClNO3PS
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
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Echothiopate chloride 相关分类

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Keywords:

Echothiopate120087-68-5EchothiophateOthersInhibitorinhibitorinhibit

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