2. Anti-infection
  3. Fungal
  4. Fosmanogepix (tautomerism)

Fosmanogepix (tautomerism)  (Synonyms: APX001 (tautomerism); E1211 (tautomerism))

目录号: HY-119726A
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摩尔计算器

Fosmanogepix tautomerism (APX001 tautomerism) 是一种广谱且口服有效的抗侵袭性真菌感染化合物。Fosmanogepix tautomerism 的靶标是真菌中糖基磷脂酰肌醇锚定甘露蛋白定位所需的保守 Gwt1 酶，这种抑制阻止了细胞壁甘露蛋白的适当定位，从而损害了细胞壁的完整性、生物膜的形成、胚管的形成和真菌的生长。Fosmanogepix tautomerism 可用于侵袭性真菌感染疾病的研究。

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Fosmanogepix (tautomerism) Chemical Structure

Fosmanogepix (tautomerism) Chemical Structure

CAS No. : 1169701-00-1

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Fosmanogepix (tautomerism) 的其他形式现货产品:

Other Forms of Fosmanogepix (tautomerism):

Fosmanogepix (tautomerism) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Fosmanogepix tautomerism (APX001 tautomerism) is a broad-spectrum and orally active anti-invasive fungal compound. Fosmanogepix tautomerism targets the conserved Gwt1 enzyme required for the localization of glycosylphosphatidylinositol-anchored mannoproteins in fungi, and inhibition prevents proper localization of cell wall mannoproteins, thereby impairing cell wall integrity, biofilm formation, germ tube formation, and fungal growth. Fosmanogepix tautomerism can be used to study invasive fungal infections[1].

分子量

468.40

Formula

C22H21N4O6P
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Fosmanogepix (tautomerism) 相关分类

  • 摩尔计算器

  • 稀释计算器

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Keywords:

Fosmanogepix (tautomerism)1169701-00-1APX001 (tautomerism) E1211 (tautomerism)FungalFungal infectioninvasivenesscell wallmannoproteinlocalizationInhibitorinhibitorinhibit

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