2. Gene
  3. SPON2 - spondin 2 Gene

SPON2 - spondin 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：spondin 2

种属: Homo sapiens

同用名: DIL1; DIL-1; MINDIN; M-SPONDIN

基因 ID: 10417 | 基因类型: protein coding

关于 SPON2

Cytogenetic location: 4p16.3 Genomic coordinates (GRCh38): 4:1,166,932-1,208,844 (from NCBI)

This gene has 22 transcripts (splice variants), 192 orthologues and 3 paralogues. Broad expression in prostate (RPKM 48.4), endometrium (RPKM 37.2) and 18 other tissues.

功能概要

预测具有抗原结合活性；脂多糖结合活性；和金属离子结合活性。预计参与细胞粘附。预计在几个过程的上游或内部起作用，包括对其他生物体的防御反应；调理作用；和细胞因子产生的正调节。位于细胞外外泌体。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable antigen binding activity; lipopolysaccharide binding activity; and metal ion binding activity. Predicted to be involved in cell adhesion. Predicted to act upstream of or within several processes, including defense response to other organism; opsonization; and positive regulation of cytokine production. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

SPON2 基因产物(3)

mRNA Protein Name
NM_001128325.3 NP_001121797.2 spondin-2 precursor
NM_001199021.2 NP_001185950.2 spondin-2 precursor
NM_012445.4 NP_036577.2 spondin-2 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SPON2 蛋白结构

Spond_N

Spond_N: Spondin_N (41 - 235)

  • 0
  • 100
  • 200
  • 300
  • 331 a.a.
蛋白主名 其他名称

spondin-2

differentially expressed in cancerous and non-cancerous lung cells 1

重组 SPON2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70142 Spondin-2/SPON2 Protein, Human (HEK293, His) AAH02707.1 (Q27-V331) ≥95%

关联疾病

疾病名称 别名
Pharyngitis

Acute Pharyngitis

Chronic Pharyngitis

Acute Sore Throat

Chronic Sore Throat

Persistent Sore Throat

Pharyngeal Diseases

Chronic Pharyn/Nasopharyngitis

Chronic Pharyngitis And Nasopharyngitis

Inflamed Throat

Pharyngeal Disease

Pharyngeal Disorder

Pharyngitis - Acute

Sore Throat - Chronic

Acute Pharyngitis Nos

Acute Sore Throat Nos

Acute Throat Inflammation

Infective Pharyngitis

Infection Of Pharynx

Acute Infective Pharyngitis

Acute Infective Pharyngitis Nos

Acute Pharyngeal Inflammation

Inflammation Of The Throat

Throat Inflammation

Throat Infection

Putrid Pharyngitis

Pharyngeal Inflammation

Pharyngitis Nos

Chronic Throat Pain

Throat Catarrh
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13699 SPON2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus SPON2 MGD MGI:1923724
Bos taurus SPON2 VGNC VGNC:35228
Macaca mulatta SPON2 VGNC VGNC:82245
Felis catus SPON2 VGNC VGNC:80010
Canis familiaris SPON2 VGNC VGNC:59026
Rattus norvegicus SPON2 RGD RGD:708584
Others SPON2 NCBI
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