2. Gene
  3. Ppif - peptidylprolyl isomerase F (cyclophilin F) Gene

Ppif - peptidylprolyl isomerase F (cyclophilin F) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CypD; CyP-D; CyP-F; PPIase

基因 ID: 105675 | 基因类型: protein coding

关于 Ppif

功能概要

Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Involved in several processes, including negative regulation of ATPase activity; positive regulation of release of cytochrome c from mitochondria; and regulation of proton transport. Acts upstream of or within apoptotic mitochondrial changes; necroptotic process; and response to oxidative stress. Located in mitochondrion. Part of mitochondrial permeability transition pore complex. Is expressed in lower jaw tooth and tooth. Orthologous to human PPIF (peptidylprolyl isomerase F). [provided by Alliance of Genome Resources, Apr 2022]

Ppif 基因产物(1)

mRNA Protein Name
NM_134084.1 NP_598845.1 peptidyl-prolyl cis-trans isomerase F, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
22726440 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within apoptotic mitochondrial changes IGI
IGI: 通过遗传相互作用推断
18350175 MGI
acts upstream of or within apoptotic process IGI
IGI: 通过遗传相互作用推断
19293339 MGI
involved in cellular response to arsenic-containing substance IMP
IMP: 通过突变表型推断
21281446 MGI
involved in cellular response to calcium ion IMP
IMP: 通过突变表型推断
15800626 MGI
involved in cellular response to hydrogen peroxide IMP
IMP: 通过突变表型推断
15800626 MGI
acts upstream of or within mitochondrial depolarization IGI
IGI: 通过遗传相互作用推断
19293339 MGI
acts upstream of or within mitochondrion organization IGI
IGI: 通过遗传相互作用推断
19293339 MGI
acts upstream of or within muscle structure development IGI
IGI: 通过遗传相互作用推断
19293339 MGI
acts upstream of or within necroptotic process IGI
IGI: 通过遗传相互作用推断
22726440 MGI
involved in negative regulation of ATP-dependent activity IMP
IMP: 通过突变表型推断
21281446 MGI
involved in negative regulation of oxidative phosphorylation IMP
IMP: 通过突变表型推断
21281446 MGI
involved in negative regulation of oxidative phosphorylation uncoupler activity IMP
IMP: 通过突变表型推断
21281446 MGI
involved in programmed cell death IMP
IMP: 通过突变表型推断
15800627 MGI
acts upstream of or within regulation of mitochondrial membrane permeability IGI
IGI: 通过遗传相互作用推断
22726440 MGI
involved in regulation of mitochondrial membrane permeability IMP
IMP: 通过突变表型推断
16103352 MGI
involved in regulation of mitochondrial membrane permeability involved in programmed necrotic cell death IMP
IMP: 通过突变表型推断
15800626 MGI
involved in regulation of proton-transporting ATPase activity, rotational mechanism IMP
IMP: 通过突变表型推断
19801635 MGI
involved in response to ischemia IMP
IMP: 通过突变表型推断
15800626 MGI
acts upstream of or within response to oxidative stress IGI
IGI: 通过遗传相互作用推断
22726440 MGI
acts upstream of or within skeletal muscle fiber differentiation IGI
IGI: 通过遗传相互作用推断
19293339 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of mitochondrial permeability transition pore complex IMP
IMP: 通过突变表型推断
31489369 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

peptidyl-prolyl cis-trans isomerase F, mitochondrial

PPIase F

cyclophilin D

cyclophilin F

mitochondrial Cyclophilin D

peptidyl-prolyl cis-trans isomerase, mitochondrial

rotamase F

Ppif 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Ppif Q99KR7 Tp53 Mus musculus P02340
Anti Bait CoIP
22726440
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10951 PPIF Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ppif NCBI NCBI:10105
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