1. Gene
  2. SCGN - secretagogin, EF-hand calcium binding protein Gene

SCGN - secretagogin, EF-hand calcium binding protein Gene

中文名称:促分泌素,EF-手钙结合蛋白

种属: Homo sapiens

同用名: SEGN; CALBL; SECRET; setagin; DJ501N12.8

基因 ID: 10590 | 基因类型: protein coding

关于 SCGN

Cytogenetic location: 6p22.2 Genomic coordinates (GRCh38): 6:25,652,215-25,701,783 (from NCBI)

This gene has 2 transcripts (splice variants), 267 orthologues and 2 paralogues. Biased expression in stomach (RPKM 11.2), colon (RPKM 8.7) and 8 other tissues.

功能概要

编码的蛋白质是一种分泌型钙结合蛋白,存在于细胞质中。它与钙结合蛋白 D-28K 和钙视网膜蛋白有关。这种蛋白质被认为与 KCL 刺激的钙流和细胞增殖有关。[RefSeq 提供,2008 年 7 月]

The encoded protein is a secreted calcium-binding protein which is found in the cytoplasm. It is related to calbindin D-28K and calretinin. This protein is thought to be involved in KCL-stimulated calcium flux and cell proliferation. [provided by RefSeq, Jul 2008]

SCGN 基因产物(1)

mRNA Protein Name
NM_006998.4 NP_008929.2 secretagogin

SCGN 蛋白结构

EF-hand_7

EF-hand_7: EF-hand domain pair (111 - 177)

EF-hand_5

EF-hand_5: EF hand (249 - 267)

  • 0
  • 100
  • 200
  • 276 a.a.
蛋白主名 其他名称

secretagogin

重组 SCGN 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71042 SCGN Protein, Human (HEK293, His) O76038 (M1-P276) ≥95%
HY-P76050 SCGN Protein, Human (His) O76038 (D2-P276) ≥95%

关联疾病

疾病名称 别名
Insulinoma

Islet Cell Adenoma

Insulin-Producing Tumor Of Islet Cells

Adenoma Islet Cell

Islet Cell Tumor

Experimental Organism Islet Cell Adenoma Neoplasm

Fanconi Renotubular Syndrome 2

FRTS2

Fanconi Renotubular Syndrome, Type 2

Neuroendocrine Tumor

Neuroendocrine Neoplasm

Neuroendocrine Tumors

Carcinoma, Neuroendocrine

Central Neurocytoma

Neurocytoma

Neurolipocytoma

Neurocytoma Central

Labyrinthitis

Labyrinthine Disorder

Inner Ear Inflammation

Otitis Interna

Labyrinth Hyperaemia

Autism Spectrum Disorder

Asd

Autism Spectrum Disorders

Autistic Continuum

Pervasive Developmental Disorder

Pervasive Development Disorder

Autistic Behavior

Autistic Disorder

Autistic

Autistic Disorder Of Childhood Onset

Infantile Autism

Childhood Autism

Kanner Syndrome

Pervasive Developmental Delay Nos

Pervasive Developmental Disorder, Not Otherwise Specified

Autism

Autistic Disorder

Autism Susceptibility 1

Childhood Autism

Autistic Disorder Of Childhood Onset

Infantile Autism

Kanner'S Syndrome

Autistic

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta SCGN VGNC VGNC:77030
Bos taurus SCGN VGNC VGNC:34337
Rattus norvegicus SCGN RGD RGD:1303281
Canis familiaris SCGN VGNC VGNC:45909
Mus musculus SCGN MGD MGI:2384873
Felis catus SCGN VGNC VGNC:64913
Others SCGN NCBI