2. Gene
  3. SCGN - secretagogin, EF-hand calcium binding protein Gene

SCGN - secretagogin, EF-hand calcium binding protein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：促分泌素，EF-手钙结合蛋白

种属: Homo sapiens

同用名: SEGN; CALBL; SECRET; setagin; DJ501N12.8

基因 ID: 10590 | 基因类型: protein coding

关于 SCGN

Cytogenetic location: 6p22.2 Genomic coordinates (GRCh38): 6:25,652,215-25,701,783 (from NCBI)

This gene has 2 transcripts (splice variants), 267 orthologues and 2 paralogues. Biased expression in stomach (RPKM 11.2), colon (RPKM 8.7) and 8 other tissues.

功能概要

编码的蛋白质是一种分泌型钙结合蛋白，存在于细胞质中。它与钙结合蛋白 D-28K 和钙视网膜蛋白有关。这种蛋白质被认为与 KCL 刺激的钙流和细胞增殖有关。[RefSeq 提供，2008 年 7 月]

The encoded protein is a secreted calcium-binding protein which is found in the cytoplasm. It is related to calbindin D-28K and calretinin. This protein is thought to be involved in KCL-stimulated calcium flux and cell proliferation. [provided by RefSeq, Jul 2008]

SCGN 基因产物(1)

mRNA Protein Name
NM_006998.4 NP_008929.2 secretagogin
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SCGN 蛋白结构

EF-hand_7

EF-hand_7: EF-hand domain pair (111 - 177)

EF-hand_5

EF-hand_5: EF hand (249 - 267)

  • 0
  • 100
  • 200
  • 276 a.a.
蛋白主名 其他名称

secretagogin

重组 SCGN 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71042 SCGN Protein, Human (HEK293, His) O76038 (M1-P276) ≥95%
HY-P76050 SCGN Protein, Human (His) O76038 (D2-P276) ≥95%

关联疾病

疾病名称 别名
Insulinoma

Islet Cell Adenoma

Insulin-Producing Tumor Of Islet Cells

Adenoma Islet Cell

Islet Cell Tumor

Experimental Organism Islet Cell Adenoma Neoplasm
Fanconi Renotubular Syndrome 2

FRTS2

Fanconi Renotubular Syndrome, Type 2
Neuroendocrine Tumor

Neuroendocrine Neoplasm

Neuroendocrine Tumors

Carcinoma, Neuroendocrine
Central Neurocytoma

Neurocytoma

Neurolipocytoma

Neurocytoma Central
Labyrinthitis

Labyrinthine Disorder

Inner Ear Inflammation

Otitis Interna

Labyrinth Hyperaemia
Autism Spectrum Disorder

Asd

Autism Spectrum Disorders

Autistic Continuum

Pervasive Developmental Disorder

Pervasive Development Disorder

Autistic Behavior

Autistic Disorder

Autistic

Autistic Disorder Of Childhood Onset

Infantile Autism

Childhood Autism

Kanner Syndrome

Pervasive Developmental Delay Nos

Pervasive Developmental Disorder, Not Otherwise Specified
Autism

Autistic Disorder

Autism Susceptibility 1

Childhood Autism

Autistic Disorder Of Childhood Onset

Infantile Autism

Kanner'S Syndrome

Autistic
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12509 SCGN Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta SCGN VGNC VGNC:77030
Bos taurus SCGN VGNC VGNC:34337
Rattus norvegicus SCGN RGD RGD:1303281
Canis familiaris SCGN VGNC VGNC:45909
Mus musculus SCGN MGD MGI:2384873
Felis catus SCGN VGNC VGNC:64913
Others SCGN NCBI
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z