ARID3B - AT-rich interaction domain 3B Gene

中文名称：AT-rich 交互域 3B

种属: Homo sapiens

同用名: BDP; DRIL2

关于 ARID3B

功能概要

该基因编码 DNA 结合蛋白 ARID (富含 AT 相互作用域) 家族的成员。编码的蛋白质与两种与视网膜母细胞瘤基因产物结合的蛋白质同源，还与小鼠 Bright 和果蝇死林格蛋白同源。该基因在染色体 1p31 上存在一个假基因。 ARID 家族的成员在胚胎模式、细胞谱系基因调控、细胞周期控制、转录调控和可能的染色质结构修饰中发挥作用。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA-binding proteins. The encoded protein is homologous with two proteins that bind to the retinoblastoma gene product, and also with the mouse Bright and Drosophila dead ringer proteins. A pseudogene on chromosome 1p31 exists for this gene. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008]