2. Gene
  3. Ankrd1 - ankyrin repeat domain 1 (cardiac muscle) Gene

Ankrd1 - ankyrin repeat domain 1 (cardiac muscle) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Alrp; CARP; Crap; MARP1

基因 ID: 107765 | 基因类型: protein coding

关于 Ankrd1

功能概要

Enables titin binding activity and transcription corepressor activity. Involved in cellular response to lipopolysaccharide and cellular response to xenobiotic stimulus. Acts upstream of or within protein kinase C signaling; regulation of transcription by RNA polymerase II; and skeletal muscle cell differentiation. Located in I band and nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; heart; male reproductive gland or organ; skeletal musculature; and somite. Human ortholog(s) of this gene implicated in congenital structural myopathy; dilated cardiomyopathy; hypertrophic cardiomyopathy; nemaline myopathy; and spinal muscular atrophy. Orthologous to human ANKRD1 (ankyrin repeat domain 1). [provided by Alliance of Genome Resources, Apr 2022]

Ankrd1 基因产物(1)

mRNA Protein Name
NM_013468.3 NP_038496.2 ankyrin repeat domain-containing protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
14741210 MGI
enables titin binding IPI
IPI: 通过物理相互作用推断
18310072 MGI
enables transcription corepressor activity IDA
IDA: 通过直接分析推断
9043061 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to lipopolysaccharide IDA
IDA: 通过直接分析推断
17239933 MGI
involved in cellular response to xenobiotic stimulus IDA
IDA: 通过直接分析推断
17239933 MGI
acts upstream of or within phospholipase C/protein kinase C signal transduction IGI
IGI: 通过遗传相互作用推断
27353086 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
9043061 MGI
acts upstream of or within skeletal muscle cell differentiation IMP
IMP: 通过突变表型推断
22147266 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in I band IDA
IDA: 通过直接分析推断
11309420 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
9382869 MGI
located in myofibril IDA
IDA: 通过直接分析推断
18310072 MGI
located in nucleus IDA
IDA: 通过直接分析推断
9382869 MGI
part of protein-containing complex IDA
IDA: 通过直接分析推断
27353086 MGI
part of transcription regulator complex IDA
IDA: 通过直接分析推断
9043061 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ankyrin repeat domain-containing protein 1

ankyrin-like repeat protein

cardiac ankyrin repeat protein

cardiac responsive adriamycin protein

Ankrd1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Ankrd1 Q9CR42 Ncl Mus musculus P09405
Anti Bait CoIP
24515436
种属内
Ankrd1 Q9CR42 Ncl Mus musculus P09405
Y2H
24515436
种属内
Ankrd1 Q9CR42 Ncl Mus musculus P09405
Anti Tag CoIP
24515436
种属内
Ankrd1 Q9CR42 Ncl Mus musculus P09405
IF
24515436
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00712 ANKRD1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ankrd1 NCBI NCBI:27063
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