Raf1 - v-raf-leukemia viral oncogene 1 Gene

中文名称：v-raf-白血病病毒致癌基因1

种属: Mus musculus

同用名: cRaf; Craf1; Raf-1; c-Raf; v-Raf; 6430402F14Rik; D830050J10Rik

关于 Raf1

功能概要

该基因编码的蛋白可启动小 GTPase 绑定活动。作用于多个过程的上游或内部，包括细胞表面受体信号通路；腺体发育；氮化合物代谢过程的正向调控。位于伪讲台。以多种结构表达，包括消化系统；中枢神经系统;早孕;泌尿生殖系统；和免疫系统。用于研究努南综合征 5. 该基因与努南综合征相关的人类直向同源基因（多个）； Noonan 综合征伴多发雀斑 2；腺癌（多发性）；和扩张型心肌病 1NN。与人 RAF1 同源（Raf-1 原癌基因，丝氨酸/苏氨酸激酶）。 [由基因组资源联盟提供，2022 年 4 月]

Enables small GTPase binding activity. Acts upstream of or within several processes, including cell surface receptor signaling pathway; gland development; and positive regulation of nitrogen compound metabolic process. Located in pseudopodium. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and immune system. Used to study Noonan syndrome 5. Human ortholog(s) of this gene implicated in Noonan syndrome (multiple); Noonan syndrome with multiple lentigines 2; adenocarcinoma (multiple); and dilated cardiomyopathy 1NN. Orthologous to human RAF1 (Raf-1 proto-oncogene, serine/threonine kinase). [provided by Alliance of Genome Resources, Apr 2022]