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  2. CDC42EP1 - CDC42 effector protein 1 Gene

CDC42EP1 - CDC42 effector protein 1 Gene

中文名称:CDC42 效应蛋白 1

种属: Homo sapiens

同用名: CEP1; BORG5; MSE55

基因 ID: 11135 | 基因类型: protein coding

关于 CDC42EP1

Cytogenetic location: 22q13.1 Genomic coordinates (GRCh38): 22:37,560,480-37,569,405 (from NCBI)

This gene has 4 transcripts (splice variants), 264 orthologues and 5 paralogues. Ubiquitous expression in stomach (RPKM 41.4), gall bladder (RPKM 17.9) and 24 other tissues.

功能概要

CDC42 是调节多种细胞活动 (包括肌动蛋白聚合) 的 Rho GTPase 家族成员。该基因编码的蛋白质是一种 CDC42 结合蛋白,可介导质膜上的肌动蛋白细胞骨架重组。这种蛋白质是分泌型的,主要存在于骨髓中。[RefSeq 提供,2008 年 7 月]

CDC42 is a member of the Rho GTPase family that regulates multiple cellular activities, including actin polymerization. The protein encoded by this gene is a CDC42 binding protein that mediates actin Cytoskeleton reorganization at the plasma membrane. This protein is secreted and is primarily found in bone marrow. [provided by RefSeq, Jul 2008]

CDC42EP1 基因产物(1)

mRNA Protein Name
NM_152243.3 NP_689449.1 cdc42 effector protein 1

CDC42EP1 蛋白结构

PBD

PBD: P21-Rho-binding domain (37 - 69)

BORG_CEP

BORG_CEP: Cdc42 effector (115 - 215)

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  • 391 a.a.
蛋白主名 其他名称

cdc42 effector protein 1

55 kDa bone marrow stromal/endothelial cell protein

直系同源

种属 基因名 来源 基因 ID
Canis familiaris CDC42EP1 VGNC VGNC:39000
Felis catus CDC42EP1 VGNC VGNC:83522
Macaca mulatta CDC42EP1 VGNC VGNC:70782
Rattus norvegicus CDC42EP1 RGD RGD:1311131
Mus musculus CDC42EP1 MGD MGI:1929763
Bos taurus CDC42EP1 VGNC VGNC:27072