FZD10 - frizzled class receptor 10 Gene

中文名称：卷曲类受体 10

种属: Homo sapiens

同用名: Fz10; FzE7; CD350; FZ-10; hFz10

关于 FZD10

功能概要

该基因是卷曲基因家族的成员。该家族的成员编码 7 次跨膜结构域蛋白，这些蛋白是信号蛋白 Wingless 型 MMTV 整合位点家族的受体。大多数 Frizzled 受体与 β-连环蛋白经典信号通路相耦合。使用阵列分析，这种无内含子基因的表达在两种原发性结肠癌病例中显着上调。[RefSeq 提供，2008 年 7 月]

This gene is a member of the Frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most Frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon Cancer. [provided by RefSeq, Jul 2008]