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  2. HILPDA - hypoxia inducible lipid droplet associated Gene

HILPDA - hypoxia inducible lipid droplet associated Gene

中文名称:缺氧诱导脂滴相关

种属: Homo sapiens

同用名: HIG2; HIG-2; C7orf68

基因 ID: 29923 | 基因类型: protein coding

关于 HILPDA

Cytogenetic location: 7q32.1 Genomic coordinates (GRCh38): 7:128,455,878-128,458,418 (from NCBI)

This gene has 4 transcripts (splice variants) and 43 orthologues. Broad expression in esophagus (RPKM 37.4), fat (RPKM 20.9) and 20 other tissues.

功能概要

启用信号受体结合活性。参与多个过程,包括自分泌信号;细胞对缺氧的反应;和脂质储存的正调节。位于多个细胞成分中,包括细胞表面;脂滴;和分泌颗粒。 [由基因组资源联盟提供,2022 年 4 月]

Enables signaling receptor binding activity. Involved in several processes, including autocrine signaling; cellular response to hypoxia; and positive regulation of lipid storage. Located in several cellular components, including cell surface; lipid droplet; and secretory granule. [provided by Alliance of Genome Resources, Apr 2022]

HILPDA 基因产物(2)

mRNA Protein Name
NM_001098786.2 NP_001092256.1 hypoxia-inducible lipid droplet-associated protein
NM_013332.4 NP_037464.1 hypoxia-inducible lipid droplet-associated protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15930302 GOA
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
15930302 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in autocrine signaling IDA
IDA: 通过直接分析推断
15930302 GOA
involved in cellular response to hypoxia IEP
IEP: 通过表达模式推断
10690527 GOA
involved in positive regulation of cell population proliferation IDA
IDA: 通过直接分析推断
15930302 GOA
involved in positive regulation of cytokine production IDA
IDA: 通过直接分析推断
20624928 GOA
involved in positive regulation of lipid storage IDA
IDA: 通过直接分析推断
20624928 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
15930302 GOA
located in extracellular space IDA
IDA: 通过直接分析推断
15930302 GOA
located in lipid droplet IDA
IDA: 通过直接分析推断
20624928 GOA
located in secretory granule IDA
IDA: 通过直接分析推断
15930302 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

HILPDA 蛋白结构

HILPDA

HILPDA: Hypoxia-inducible lipid droplet-associated (1 - 63)

  • 0
  • 63 a.a.
蛋白主名 其他名称

hypoxia-inducible lipid droplet-associated protein

hypoxia inducible gene 2

HILPDA 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
HILPDA Q9Y5L2 GET3 Homo sapiens O43681 25416956
种属内
HILPDA Q9Y5L2 GET3 Homo sapiens O43681 25416956
种属内
HILPDA Q9Y5L2 GET3 Homo sapiens O43681 25416956
种属内
HILPDA Q9Y5L2 FZD10 Homo sapiens Q9ULW2 15930302
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta HILPDA VGNC VGNC:73451
Rattus norvegicus HILPDA RGD RGD:2319900
Mus musculus HILPDA MGD MGI:1916823