2. Gene
  3. PTH2 - parathyroid hormone 2 Gene

PTH2 - parathyroid hormone 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：甲状旁腺激素 2

种属: Homo sapiens

同用名: TIP39

基因 ID: 113091 | 基因类型: protein coding

关于 PTH2

Cytogenetic location: 19q13.33 Genomic coordinates (GRCh38): 19:49,422,419-49,423,441 (from NCBI)

This gene has 1 transcript (splice variant) and 150 orthologues.

功能概要

该基因编码与甲状旁腺激素具有序列相似性的肽激素的前体。该基因在大脑的不同区域表达，在脑垂体激素的释放、焦虑和伤害感受中发挥作用。编码的前体蛋白经过蛋白水解处理以产生具有生物活性的神经肽。[RefSeq 提供，2015 年 7 月]

This gene encodes the precursor of a peptide hormone that shares sequence similarity with the parathyroid hormone. This gene is expressed in various regions of the brain where it plays a role in the release of pituitary Hormones, anxiety and nociception. The encoded precursor protein is proteolytically processed to generate the biologically active neuropeptide. [provided by RefSeq, Jul 2015]

PTH2 基因产物(1)

mRNA Protein Name
NM_178449.4 NP_848544.1 tuberoinfundibular peptide of 39 residues preproprotein

PTH2 蛋白结构

TIP39

TIP39: TIP39 peptide (49 - 99)

  • 0
  • 100 a.a.
蛋白主名 其他名称

tuberoinfundibular peptide of 39 residues

tuberoinfundibular 39 residue protein

关联疾病

疾病名称 别名
Polyomavirus-Associated Nephropathy

Polyomavirus Associated Nephropathy

Pvan
Benign Chronic Pemphigus

Hailey-Hailey Disease

Pemphigus, Benign Familial

Familial Benign Pemphigus

Benign Familial Pemphigus

Familial Benign Chronic Pemphigus

BCPM

HHD

Benign Chronic Familial Pemphigus Of Hailey-Hailey

Pemphigus, Chronic, Benign
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P1852 TIP 39, Tuberoinfundibular Neuropeptide Activator 99.84% 否
HY-RS11396 PTH2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS11397 PTH2R Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus PTH2 VGNC VGNC:64429
Rattus norvegicus PTH2 RGD RGD:1559447
Bos taurus PTH2 VGNC VGNC:33515
Mus musculus PTH2 MGD MGI:2152297
Canis familiaris PTH2 VGNC VGNC:45155
Macaca mulatta PTH2 VGNC VGNC:76577
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