1. Gene
  2. Adam9 - a disintegrin and metallopeptidase domain 9 (meltrin gamma) Gene

Adam9 - a disintegrin and metallopeptidase domain 9 (meltrin gamma) Gene

种属: Mus musculus

同用名: MDC9; Mltng; mKIAA0021

基因 ID: 11502 | 基因类型: protein coding

关于 Adam9

功能概要

Enables SH3 domain binding activity; metalloendopeptidase activity; and protein kinase C binding activity. Involved in several processes, including cell adhesion mediated by integrin; membrane protein ectodomain proteolysis; and positive regulation of membrane protein ectodomain proteolysis. Located in several cellular components, including cell surface; extracellular space; and plasma membrane. Is intrinsic component of external side of plasma membrane. Is expressed in foregut-midgut junction. Used to study cone-rod dystrophy 9. Human ortholog(s) of this gene implicated in cone-rod dystrophy 9. Orthologous to human ADAM9 (ADAM metallopeptidase domain 9). [provided by Alliance of Genome Resources, Apr 2022]

Adam9 基因产物(2)

mRNA Protein Name
NM_001270996.1 NP_001257925.1 disintegrin and metalloproteinase domain-containing protein 9 isoform 1 precursor
NM_007404.2 NP_031430.2 disintegrin and metalloproteinase domain-containing protein 9 isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables SH3 domain binding IDA
IDA: 通过直接分析推断
8647900 MGI
enables metalloendopeptidase activity IDA
IDA: 通过直接分析推断
22480688 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10531379 MGI
enables protein kinase C binding IPI
IPI: 通过物理相互作用推断
9857183 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell adhesion mediated by integrin IDA
IDA: 通过直接分析推断
10825303 MGI
involved in cell migration IDA
IDA: 通过直接分析推断
10825303 MGI
involved in membrane protein ectodomain proteolysis IDA
IDA: 通过直接分析推断
19273593 MGI
involved in positive regulation of membrane protein ectodomain proteolysis IDA
IDA: 通过直接分析推断
9857183 MGI
involved in response to glucocorticoid IMP
IMP: 通过突变表型推断
16311053 MGI
involved in transforming growth factor beta receptor signaling pathway IMP
IMP: 通过突变表型推断
11955914 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
8647900 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
15739225 MGI
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
9920899 MGI
located in extracellular space IMP
IMP: 通过突变表型推断
9920899 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
15739225 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

disintegrin and metalloproteinase domain-containing protein 9

a disintegrin and metalloproteinase domain 9 (meltrin gamma)

metalloprotease/disintegrin/cysteine-rich protein 9

myeloma cell metalloproteinase

重组 Adam9 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75531 ADAM9 Protein, Mouse (HEK293, His) Q61072 (G30-D697) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Adam9 NCBI NCBI:8754