2. Gene
  3. Bcl3 - B cell leukemia/lymphoma 3 Gene

Bcl3 - B cell leukemia/lymphoma 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Bcl-3

基因 ID: 12051 | 基因类型: protein coding

关于 Bcl3

功能概要

Enables transcription coactivator activity. Acts upstream of or within several processes, including defense response to Other organism; hematopoietic or lymphoid organ development; and regulation of gene expression. Predicted to be located in several cellular components, including cytosol; midbody; and nucleoplasm. Predicted to be part of Bcl3-Bcl10 complex and Bcl3/NF-kappaB2 complex. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; immune system; and liver and biliary system. Orthologous to human BCL3 (BCL3 transcription coactivator). [provided by Alliance of Genome Resources, Apr 2022]

Bcl3 基因产物(1)

mRNA Protein Name
NM_033601.3 NP_291079.2 B-cell lymphoma 3 protein homolog
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12730195 MGI
enables transcription coactivator activity IDA
IDA: 通过直接分析推断
16081776 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of T cell apoptotic process IGI
IGI: 通过遗传相互作用推断
16832056 MGI
acts upstream of T cell apoptotic process IMP
IMP: 通过突变表型推断
16832056 MGI
acts upstream of or within T-helper 1 type immune response IMP
IMP: 通过突变表型推断
9009202 MGI
acts upstream of or within T-helper 2 cell differentiation IMP
IMP: 通过突变表型推断
16081776 MGI
acts upstream of or within antimicrobial humoral response IMP
IMP: 通过突变表型推断
9009202 MGI
acts upstream of or within defense response to bacterium IMP
IMP: 通过突变表型推断
9009202 MGI
acts upstream of or within defense response to protozoan IMP
IMP: 通过突变表型推断
9009202 MGI
acts upstream of or within extracellular matrix organization IMP
IMP: 通过突变表型推断
10586052 MGI
acts upstream of or within follicular dendritic cell differentiation IMP
IMP: 通过突变表型推断
10586052 MGI
acts upstream of or within germinal center formation IMP
IMP: 通过突变表型推断
9009202 MGI
acts upstream of or within humoral immune response mediated by circulating immunoglobulin IMP
IMP: 通过突变表型推断
9009202 MGI
acts upstream of or within marginal zone B cell differentiation IMP
IMP: 通过突变表型推断
9009202 MGI
acts upstream of or within negative regulation of T cell apoptotic process IGI
IGI: 通过遗传相互作用推断
16832056 MGI
acts upstream of or within negative regulation of T cell apoptotic process IMP
IMP: 通过突变表型推断
16832056 MGI
acts upstream of or within negative regulation of tumor necrosis factor production IMP
IMP: 通过突变表型推断
15465827 MGI
acts upstream of or within positive regulation of interleukin-10 production IMP
IMP: 通过突变表型推断
15465827 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
16081776 MGI
acts upstream of or within positive regulation of type II interferon production IMP
IMP: 通过突变表型推断
16790793 MGI
acts upstream of or within spleen development IMP
IMP: 通过突变表型推断
10586052 MGI
acts upstream of type II interferon production IMP
IMP: 通过突变表型推断
16790793 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

B-cell lymphoma 3 protein homolog

B-cell CLL/lymphoma 3

Bcl3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Bcl3 Q9Z2F6 Cyld Mus musculus Q80TQ2
Anti Bait CoIP
16713561
种属内
Bcl3 Q9Z2F6 Cyld Mus musculus Q80TQ2
Y2H
16713561
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-14454 TPh A Inhibitor 99.81% 否
HY-152177 JS6 Inhibitor 99.67% 否
HY-RS01437 BCL3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bcl3 NCBI NCBI:602
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