1. Gene
  2. Cspg4 - chondroitin sulfate proteoglycan 4 Gene

Cspg4 - chondroitin sulfate proteoglycan 4 Gene

种属: Mus musculus

同用名: AN2; NG2; Cspg4a; 4732461B14Rik

基因 ID: 121021 | 基因类型: protein coding

关于 Cspg4

功能概要

Enables coreceptor activity. Acts upstream of or within several processes, including platelet-derived growth factor receptor signaling pathway; positive regulation of MAPK cascade; and ruffle assembly. Located in plasma membrane and ruffle. Is expressed in several structures, including brain; jaw; respiratory system; retina; and skeleton. Human ortholog(s) of this gene implicated in relapsing-remitting multiple sclerosis. Orthologous to human CSPG4 (chondroitin sulfate proteoglycan 4). [provided by Alliance of Genome Resources, Apr 2022]

Cspg4 基因产物(1)

mRNA Protein Name
NM_139001.2 NP_620570.2 chondroitin sulfate proteoglycan 4 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables coreceptor activity IDA
IDA: 通过直接分析推断
26437238 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12458226 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within glial cell migration IDA
IDA: 通过直接分析推断
10366628 MGI
acts upstream of or within platelet-derived growth factor receptor signaling pathway IDA
IDA: 通过直接分析推断
26437238 MGI
acts upstream of or within positive regulation of MAPK cascade IMP
IMP: 通过突变表型推断
10036240 MGI
acts upstream of or within ruffle assembly IDA
IDA: 通过直接分析推断
26437238 MGI
acts upstream of or within substrate-dependent cell migration IGI
IGI: 通过遗传相互作用推断
26437238 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell projection IDA
IDA: 通过直接分析推断
23447615 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
11668599 MGI
located in ruffle IDA
IDA: 通过直接分析推断
26437238 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

chondroitin sulfate proteoglycan 4

AN2 proteoglycan

AN2/NG2 proteoglycan

chondroitin sulfate proteoglycan NG2

nerve/glial antigen 2

proteoglycan AN2

Cspg4 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Cspg4 Q8VHY0 Grip1 Mus musculus Q925T6 12458226
种属内
Cspg4 Q8VHY0 Grip1 Mus musculus Q925T6 12458226
种属内
Cspg4 Q8VHY0 Grip1 Mus musculus Q925T6 12458226
种属内
Cspg4 Q8VHY0 Gria2 Mus musculus P23819 12458226
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cspg4 NCBI NCBI:1464
Macaca fascicularis Cspg4 NCBI