2. Gene
  3. Cobl - cordon-bleu WH2 repeat Gene

Cobl - cordon-bleu WH2 repeat Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 12808 | 基因类型: protein coding

关于 Cobl

功能概要

Enables actin monomer binding activity. Involved in actin filament organization; collateral sprouting in absence of injury; and positive regulation of cell projection organization. Acts upstream of or within several processes, including chordate embryonic development; liver development; and notochord development. Located in several cellular components, including growth cone; ruffle; and terminal web. Colocalizes with actin filament. Is expressed in several structures, including central nervous system; chordamesoderm; embryo mesenchyme; gut; and nose. Orthologous to human COBL (cordon-bleu WH2 repeat protein). [provided by Alliance of Genome Resources, Apr 2022]

Cobl 基因产物(9)

mRNA Protein Name
NM_001282993.2 NP_001269922.1 protein cordon-bleu isoform 2
NM_001282994.2 NP_001269923.1 protein cordon-bleu isoform 3
NM_001401095.1 NP_001388024.1 protein cordon-bleu isoform 4
NM_001401096.1 NP_001388025.1 protein cordon-bleu isoform 5
NM_001401097.1 NP_001388026.1 protein cordon-bleu isoform 6
NM_001401098.1 NP_001388027.1 protein cordon-bleu isoform 7
NM_001401099.1 NP_001388028.1 protein cordon-bleu isoform 8
NM_001401100.1 NP_001388029.1 protein cordon-bleu isoform 9
NM_172496.4 NP_766084.3 protein cordon-bleu isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin monomer binding IDA
IDA: 通过直接分析推断
17956734 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
17956734 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within actin cytoskeleton organization IMP
IMP: 通过突变表型推断
29891944 MGI
involved in actin filament network formation IDA
IDA: 通过直接分析推断
17956734 MGI
involved in actin filament polymerization IMP
IMP: 通过突变表型推断
17956734 MGI
involved in collateral sprouting in absence of injury IMP
IMP: 通过突变表型推断
17956734 MGI
involved in digestive tract development IEP
IEP: 通过表达模式推断
7586755 MGI
involved in embryonic axis specification IEP
IEP: 通过表达模式推断
7586755 MGI
involved in floor plate development IEP
IEP: 通过表达模式推断
7586755 MGI
involved in liver development IEP
IEP: 通过表达模式推断
7586755 MGI
acts upstream of or within neural tube closure IGI
IGI: 通过遗传相互作用推断
14512015 MGI
involved in notochord development IEP
IEP: 通过表达模式推断
7586755 MGI
involved in positive regulation of dendrite development IDA
IDA: 通过直接分析推断
21725280 MGI
involved in positive regulation of ruffle assembly IDA
IDA: 通过直接分析推断
17956734 MGI
involved in somite specification IEP
IEP: 通过表达模式推断
7586755 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
colocalizes with actin filament IDA
IDA: 通过直接分析推断
17956734 MGI
located in axon IDA
IDA: 通过直接分析推断
17956734 MGI
located in axonal growth cone IDA
IDA: 通过直接分析推断
17956734 MGI
located in cell cortex IDA
IDA: 通过直接分析推断
21725280 MGI
located in dendrite IDA
IDA: 通过直接分析推断
17956734 MGI
located in dendritic growth cone IDA
IDA: 通过直接分析推断
17956734 MGI
located in membrane IDA
IDA: 通过直接分析推断
21725280 MGI
located in neuronal cell body IDA
IDA: 通过直接分析推断
17956734 MGI
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
21725280 MGI
located in ruffle IDA
IDA: 通过直接分析推断
17956734 MGI
located in terminal web IDA
IDA: 通过直接分析推断
22114352 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein cordon-bleu

Cobl 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Cobl Q5NBX1 Pacsin1 Rattus norvegicus Q9Z0W5
Anti Tag CoIP
21725280
种属间
Cobl Q5NBX1 Pacsin1 Rattus norvegicus Q9Z0W5
Far-WB
21725280
种属间
Cobl Q5NBX1 Pacsin1 Rattus norvegicus Q9Z0W5
Pull Down
21725280
种属间
Cobl Q5NBX1 Pacsin2 Rattus norvegicus Q9QY17
Far-WB
21725280
种属间
Cobl Q5NBX1 Pacsin2 Rattus norvegicus Q9QY17
Pull Down
21725280
种属间
Cobl Q5NBX1 Pacsin3 Rattus norvegicus Q5I2Z0
Far-WB
21725280
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02947 COBL Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cobl NCBI NCBI:23242
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z