2. Gene
  3. Pacsin1 - protein kinase C and casein kinase substrate in neurons 1 Gene

Pacsin1 - protein kinase C and casein kinase substrate in neurons 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 29704 | 基因类型: protein coding

关于 Pacsin1

功能概要

Enables phospholipid binding activity. Involved in several processes, including plasma membrane tubulation; positive regulation of dendrite development; and regulation of postsynaptic neurotransmitter receptor internalization. Located in axon terminus; perinuclear region of cytoplasm; and plasma membrane. Is active in glutamatergic synapse and postsynaptic density membrane. Orthologous to human PACSIN1 (protein kinase C and Casein Kinase substrate in neurons 1). [provided by Alliance of Genome Resources, Apr 2022]

Pacsin1 基因产物(1)

mRNA Protein Name
NM_017294.1 NP_058990.1 protein kinase C and casein kinase substrate in neurons protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables phospholipid binding IDA
IDA: 通过直接分析推断
22355135 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
9950691 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cytoskeleton organization IDA
IDA: 通过直接分析推断
9950691 RGD
involved in neuron projection morphogenesis IMP
IMP: 通过突变表型推断
22355135 RGD
involved in plasma membrane tubulation IMP
IMP: 通过突变表型推断
22355135 RGD
involved in positive regulation of dendrite development IDA
IDA: 通过直接分析推断
21725280 RGD
involved in protein localization to plasma membrane IDA
IDA: 通过直接分析推断
21725280 RGD
involved in regulation of postsynaptic neurotransmitter receptor internalization IDA
IDA: 通过直接分析推断
16617342 RGD
involved in regulation of postsynaptic neurotransmitter receptor internalization IMP
IMP: 通过突变表型推断
16617342 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon terminus IDA
IDA: 通过直接分析推断
22355135 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
16617342 RGD
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
16617342 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
21725280 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
21725280 RGD
is active in postsynaptic density membrane IDA
IDA: 通过直接分析推断
16617342 RGD
located in synapse IDA
IDA: 通过直接分析推断
21725280 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein kinase C and casein kinase substrate in neurons protein 1

dynamin PRD-interacting protein

dynamin proline-rich domain-interacting protein

sdpI

synaptic, dynamin-associated protein I

syndapin-1

syndapin-I

Pacsin1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Cross Pacsin1 Q9Z0W5 Cobl Mus musculus Q5NBX1
Pull Down
21725280
Cross Pacsin1 Q9Z0W5 Cobl Mus musculus Q5NBX1
Y2H
17956734
Intra Pacsin1 Q9Z0W5 Cobl Rattus norvegicus D3ZUI5
Anti Bait CoIP
21725280
Intra Pacsin1 Q9Z0W5 Cobl Rattus norvegicus D3ZUI5
Density Sedimentation
21725280
Cross Pacsin1 Q9Z0W5 NCKIPSD Homo sapiens Q9NZQ3
Y2H
16999739
Cross Pacsin1 Q9Z0W5 NCKIPSD Homo sapiens Q9NZQ3
Anti Bait CoIP
16999739
Cross Pacsin1 Q9Z0W5 NCKIPSD Homo sapiens Q9NZQ3
Pull Down
16999739
Intra Pacsin1 Q9Z0W5 Dnm1 Rattus norvegicus P21575
Anti Bait CoIP
17437541
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09957 PACSIN1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pacsin1 NCBI NCBI:29993
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z