2. Gene
  3. Csf2 - colony stimulating factor 2 (granulocyte-macrophage) Gene

Csf2 - colony stimulating factor 2 (granulocyte-macrophage) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CSF; Csfgm; GMCSF; Gm-CSf; MGI-IGM

基因 ID: 12981 | 基因类型: protein coding

关于 Csf2

功能概要

Enables cytokine activity. Acts upstream of or within several processes, including embryonic placenta development; myeloid leukocyte differentiation; and positive regulation of cell population proliferation. Located in extracellular space. Is expressed in several structures, including genitourinary system; hemolymphoid system; labyrinthine zone; liver; and lung. Used to study pulmonary alveolar proteinosis. Human ortholog(s) of this gene implicated in acute myeloid leukemia; juvenile myelomonocytic leukemia; neutropenia; pulmonary alveolar proteinosis; and visceral leishmaniasis. Orthologous to human CSF2 (colony stimulating factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Csf2 基因产物(1)

mRNA Protein Name
NM_009969.4 NP_034099.2 granulocyte-macrophage colony-stimulating factor precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cytokine activity IDA
IDA: 通过直接分析推断
1350248 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of cell population proliferation IDA
IDA: 通过直接分析推断
1350248 MGI
acts upstream of or within embryonic placenta development IMP
IMP: 通过突变表型推断
19228596 MGI
acts upstream of or within monocyte differentiation IDA
IDA: 通过直接分析推断
19109256 MGI
acts upstream of or within myeloid dendritic cell differentiation IDA
IDA: 通过直接分析推断
12021780 MGI
acts upstream of or within neutrophil differentiation IDA
IDA: 通过直接分析推断
19109256 MGI
acts upstream of or within positive regulation of cell population proliferation IDA
IDA: 通过直接分析推断
1350248 MGI
acts upstream of or within regulation of cell population proliferation IGI
IGI: 通过遗传相互作用推断
10678181 MGI
acts upstream of or within regulation of gene expression IDA
IDA: 通过直接分析推断
9697835 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
19228596 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
7690439 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

granulocyte-macrophage colony-stimulating factor

colony-stimulating factor

granulocyte-macrophage colony stimulating factor 2

put. GM-CSF

重组 Csf2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7069 GM-CSF Protein, Mouse (CHO) Q14AD9 (A18-K141) ≥95%
HY-P7361 GM-CSF Protein, Mouse Q14AD9 (A18-K141) ≥95%
HY-P70623 GM-CSF Protein, Mouse (HEK293, His) P01587 (A18-K141) ≥95%
HY-P73082 GM-CSF Protein, Mouse (HEK293, Fc) P01587 (A18-K141) ≥95%

相关产品

Clinical Phase
抗体抑制剂 (2)
目录号 产品名 作用方式
纯度 Phase
HY-P99207 Lenzilumab 99.64% Phase 3
HY-P99307 Namilumab Inhibitor 99.47% Phase 2
Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N7038A Phytohemagglutinin P Activator / 否
HY-RS03231 CSF2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS03232 CSF2RA Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS03233 CSF2RB Human Pre-designed siRNA Set A Pre-designed Sets / 否
抗体抑制剂 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990094 Trabikibart 99.17% 否
HY-P990975 Birinkibart / 否
HY-P990381 Anti-CSF2/GM-CSF Antibody Inhibitor / 否
HY-P990382 Anti-CSF2Rb/CD131 Antibody (CSL311) Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Csf2 NCBI NCBI:1437
Canis familiaris Csf2 NCBI NCBI:403923
Macaca fascicularis Csf2 NCBI NCBI:102118747
Susscrofa domestica Csf2 NCBI
Rattus norvegicus Csf2 NCBI NCBI:116630
Macaca mulatta Csf2 NCBI NCBI:574371
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