2. Gene
  3. Csf2 - colony stimulating factor 2 Gene

Csf2 - colony stimulating factor 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Gmcsf; Gm-csf

基因 ID: 116630 | 基因类型: protein coding

关于 Csf2

功能概要

Enables cytokine activity. Involved in several processes, including cellular response to lipopolysaccharide; macrophage activation; and response to silicon dioxide. Located in extracellular space. Used to study Parkinsonism and myocardial infarction. Biomarker of abdominal aortic aneurysm; interstitial cystitis; and lung disease (multiple). Human ortholog(s) of this gene implicated in acute myeloid leukemia; juvenile myelomonocytic leukemia; neutropenia; pulmonary alveolar proteinosis; and visceral leishmaniasis. Orthologous to human CSF2 (colony stimulating factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Csf2 基因产物(1)

mRNA Protein Name
NM_053852.1 NP_446304.1 granulocyte-macrophage colony-stimulating factor precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cytokine activity IDA
IDA: 通过直接分析推断
8535150 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
18387647 RGD
involved in dendritic cell differentiation IDA
IDA: 通过直接分析推断
8535150 RGD
involved in epithelial fluid transport IDA
IDA: 通过直接分析推断
14504066 RGD
involved in histamine secretion IDA
IDA: 通过直接分析推断
9685678 RGD
involved in positive regulation of cell migration IMP
IMP: 通过突变表型推断
8304053 RGD
involved in regulation of circadian sleep/wake cycle, sleep IMP
IMP: 通过突变表型推断
12047622 RGD
involved in response to fluid shear stress IEP
IEP: 通过表达模式推断
15010288 RGD
involved in response to silicon dioxide IEP
IEP: 通过表达模式推断
21505002 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular region IDA
IDA: 通过直接分析推断
16673407 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
21442011 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

granulocyte-macrophage colony-stimulating factor

CSF

colony stimulating factor 2 (granulocyte-macrophage)

colony-stimulating factor

重组 Csf2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7094 GM-CSF Protein, Rat (CHO) P48750 (A18-K144) ≥95%
HY-P72629 GM-CSF Protein, Rat (HEK293, His) P48750 (A18-K144) ≥95%

相关产品

Clinical Phase
抗体抑制剂 (2)
目录号 产品名 作用方式
纯度 Phase
HY-P99207 Lenzilumab 99.64% Phase 3
HY-P99307 Namilumab Inhibitor 99.47% Phase 2
Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N7038A Phytohemagglutinin P Activator / 否
HY-RS03231 CSF2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS03232 CSF2RA Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS03233 CSF2RB Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Csf2 NCBI NCBI:1437
Canis familiaris Csf2 NCBI NCBI:403923
Macaca fascicularis Csf2 NCBI NCBI:102118747
Mus musculus Csf2 NCBI NCBI:12981
Susscrofa domestica Csf2 NCBI
Macaca mulatta Csf2 NCBI NCBI:574371
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