2. Gene
  3. Efna5 - ephrin A5 Gene

Efna5 - ephrin A5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: AL-1; Epl7; RAGS; EFL-5; LERK-7; Ephrin-A5

基因 ID: 13640 | 基因类型: protein coding

关于 Efna5

功能概要

Enables chemorepellent activity; Ephrin Receptor binding activity; and neurotrophin TrkB receptor binding activity. Involved in several processes, including Ephrin Receptor signaling pathway; positive regulation of nervous system development; and synaptic membrane adhesion. Acts upstream of or within cellular response to follicle-stimulating hormone stimulus; cellular response to forskolin; and retinal ganglion cell axon guidance. Located in adherens junction; basement membrane; and plasma membrane. Is active in GABA-ergic synapse. Is expressed in several structures, including alimentary system; central nervous system; embryo ectoderm; limb; and sensory organ. Used to study anencephaly. Orthologous to human EFNA5 (ephrin A5). [provided by Alliance of Genome Resources, Apr 2022]

Efna5 基因产物(3)

mRNA Protein Name
NM_001413234.1 NP_001400163.1 ephrin-A5 isoform 3
NM_010109.4 NP_034239.1 ephrin-A5 isoform 2 precursor
NM_207654.3 NP_997537.1 ephrin-A5 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chemorepellent activity IDA
IDA: 通过直接分析推断
15996548 MGI
enables ephrin receptor binding IPI
IPI: 通过物理相互作用推断
9053851 MGI
enables neurotrophin TRKB receptor binding IPI
IPI: 通过物理相互作用推断
19036963 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9883724 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within axon guidance IDA
IDA: 通过直接分析推断
9614241 MGI
acts upstream of or within axon guidance IMP
IMP: 通过突变表型推断
11222144 MGI
acts upstream of or within cellular response to follicle-stimulating hormone stimulus IDA
IDA: 通过直接分析推断
23242526 MGI
acts upstream of or within cellular response to forskolin IDA
IDA: 通过直接分析推断
23242526 MGI
involved in collateral sprouting IDA
IDA: 通过直接分析推断
19036963 MGI
involved in ephrin receptor signaling pathway IDA
IDA: 通过直接分析推断
9053851 MGI
involved in positive regulation of collateral sprouting IMP
IMP: 通过突变表型推断
19036963 MGI
involved in positive regulation of peptidyl-tyrosine phosphorylation IDA
IDA: 通过直接分析推断
17448994 MGI
involved in positive regulation of synapse assembly IDA
IDA: 通过直接分析推断
19036963 MGI
involved in regulation of GTPase activity IDA
IDA: 通过直接分析推断
17448994 MGI
involved in regulation of actin cytoskeleton organization IDA
IDA: 通过直接分析推断
17448994 MGI
involved in regulation of cell-cell adhesion IDA
IDA: 通过直接分析推断
11089974 MGI
involved in regulation of insulin secretion involved in cellular response to glucose stimulus IMP
IMP: 通过突变表型推断
17448994 MGI
acts upstream of or within retinal ganglion cell axon guidance IDA
IDA: 通过直接分析推断
15996548 MGI
involved in synaptic membrane adhesion IDA
IDA: 通过直接分析推断
22275477 MGI
involved in synaptic membrane adhesion IEP
IEP: 通过表达模式推断
22275477 MGI
involved in synaptic membrane adhesion IMP
IMP: 通过突变表型推断
22275477 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in GABA-ergic synapse IDA
IDA: 通过直接分析推断
22275477 MGI
is active in GABA-ergic synapse IEP
IEP: 通过表达模式推断
22275477 MGI
is active in GABA-ergic synapse IMP
IMP: 通过突变表型推断
22275477 MGI
located in adherens junction IDA
IDA: 通过直接分析推断
23242526 MGI
located in basement membrane IDA
IDA: 通过直接分析推断
23242526 MGI
located in cell periphery IDA
IDA: 通过直接分析推断
23242526 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
17448994 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ephrin-A5

EPH-related receptor tyrosine kinase ligand 7

重组 Efna5 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70194 Ephrin-A5/EFNA5 Protein, Mouse (HEK293, His) O08543 (Q21-Q206) ≥95%
HY-P75232 Ephrin-A5/EFNA5 Protein, Mouse (HEK293, Fc) O08543 (Q21-N203) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04196 EFNA5 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Efna5 NCBI NCBI:1946
Canis familiaris Efna5 NCBI NCBI:608458
Rattus norvegicus Efna5 NCBI NCBI:116683
Macaca mulatta Efna5 NCBI NCBI:704351
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