2. Gene
  3. BEND2 - BEN domain containing 2 Gene

BEND2 - BEN domain containing 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 BEN 域 2

种属: Homo sapiens

同用名: CXorf20

基因 ID: 139105 | 基因类型: protein coding

关于 BEND2

This gene has 2 transcripts (splice variants), 188 orthologues and 2 paralogues. Restricted expression toward testis (RPKM 2.6).

功能概要

该基因编码的蛋白质在 C 端有两个 BEN 结构域。这些结构域存在于参与染色质重组或转录过程中发生的蛋白质和 DNA 相互作用的蛋白质中。可变剪接导致多个转录本变体。[RefSeq 提供，2011 年 8 月]

This gene encodes a protein which has two BEN domains in the C-terminus. These domains are found in proteins which participate in protein and DNA interactions which occur during chromatin restructuring or transcription. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

BEND2 基因产物(2)

mRNA Protein Name
NM_001184767.2 NP_001171696.1 BEN domain-containing protein 2 isoform 2
NM_153346.5 NP_699177.2 BEN domain-containing protein 2 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

BEND2 蛋白结构

(84 - 126)

BEN

BEN: BEN domain (503 - 573)

BEN

BEN: BEN domain (689 - 763)

  • 0
  • 200
  • 400
  • 600
  • 799 a.a.
蛋白主名 其他名称

BEN domain-containing protein 2

BEND2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra BEND2 Q8NDZ0 LHX2 Homo sapiens P50458
Y2H Prey Pooling
32296183
Intra BEND2 Q8NDZ0 LHX2 Homo sapiens P50458
Y2H Array
32296183
Intra BEND2 Q8NDZ0 ANAPC11 Homo sapiens Q9NYG5-2
Validated Y2H
32296183
Intra BEND2 Q8NDZ0 ANAPC11 Homo sapiens Q9NYG5-2
Y2H Prey Pooling
32296183
Intra BEND2 Q8NDZ0 PRR20D Homo sapiens P86480
Y2H Prey Pooling
32296183
Intra BEND2 Q8NDZ0 PRR20D Homo sapiens P86480
Y2H Array
32296183
Intra BEND2 Q8NDZ0 ZMYM6 Homo sapiens O95789-4
Y2H Array
32296183
Intra BEND2 Q8NDZ0 ZMYM6 Homo sapiens O95789-4
Y2H Prey Pooling
32296183
Intra BEND2 Q8NDZ0 SF3A2 Homo sapiens Q15428
Y2H Prey Pooling
32296183
Intra BEND2 Q8NDZ0 SF3A2 Homo sapiens Q15428
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Astroblastoma, Mn1-Altered

Cns High-Grade Neuroepithelial Tumors With Mn1 Alteration
Astroblastoma

Cerebral Astroblastoma
Central Nervous System Neuroblastoma
Cns Neuroblastoma With Foxr2 Activation

Central Nervous System Neuroblastoma With Foxr2 Activation

Cns Nb-Foxr2

Cns Neuroblastoma, Foxr2-Activated
Central Nervous System Germ Cell Tumor

Central Nervous System Germ Cell Tumour

Germ Cell Tumor Of The Cns

Germ Cell Tumour Of The Cns
Rela Fusion-Positive Ependymoma

Supratentorial C11orf95-Rela Fused Ependymoma

C11orf95 Fusion-Positive Supratentorial Ependymoma
Tanycytic Ependymoma
Anaplastic Pleomorphic Xanthoastrocytoma
Supratentorial Ependymoma
High Grade Ependymoma

Ependymal Neoplasm

Ependymal Tumors

Malignant Ependymoma

Ependymal Tumor

Anaplastic Ependymoma

Experimental Organism Malignant Ependymoma

Ependymoma Of Brain
Cerebellar Astrocytoma

Astrocytoma Of Cerebellum
Anaplastic Ependymoma

Ependymoma, Anaplastic

Undifferentiated Ependymoma
Cerebral Ventricle Cancer

Cerebral Ventricle Neoplasms

Cerebral Ventricle Neoplasm

Intraventricular Tumor Of Brain
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01468 BEND2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus BEND2 VGNC VGNC:56521
Mus musculus BEND2 MGD MGI:3705232
Macaca mulatta BEND2 VGNC VGNC:70141
Canis familiaris BEND2 VGNC VGNC:53707
Rattus norvegicus BEND2 RGD RGD:7741042
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