2. Gene
  3. Cacng8 - calcium voltage-gated channel auxiliary subunit gamma 8 Gene

Cacng8 - calcium voltage-gated channel auxiliary subunit gamma 8 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 140729 | 基因类型: protein coding

关于 Cacng8

功能概要

Voltage-dependent calcium channels couple membrane depolarization in a number of cellular processes. These activities are regulated by distinct channels composed of the pore-forming alpha-1 subunit and the modulatory beta, alpha-2/delta and gamma subunits. The protein encoded by this gene represents one of the gamma subunits. It is an integral membrane protein that is thought to stabilize the Calcium Channel in an inactive (closed) state. This gene is located in a cluster with two similar gamma subunit-encoding genes on chromosome 1. The mRNA for this gene is believed to initiate translation from a non-AUG (CUG) start codon. [provided by RefSeq, Jul 2008]

Cacng8 基因产物(1)

mRNA Protein Name
NM_080696.2 NP_542427.1 voltage-dependent calcium channel gamma-8 subunit
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ionotropic glutamate receptor binding IDA
IDA: 通过直接分析推断
12771129 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
24418105 RGD
enables protein phosphatase 2B binding IPI
IPI: 通过物理相互作用推断
24418105 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of AMPA receptor activity IDA
IDA: 通过直接分析推断
12771129 RGD
involved in regulation of AMPA receptor activity IDA
IDA: 通过直接分析推断
17880894 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of AMPA glutamate receptor complex IDA
IDA: 通过直接分析推断
19265014 RGD
located in dendrite membrane IDA
IDA: 通过直接分析推断
24418105 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
12771129 RGD
is active in postsynaptic density membrane IDA
IDA: 通过直接分析推断
12771129 RGD
located in postsynaptic membrane IDA
IDA: 通过直接分析推断
24418105 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

voltage-dependent calcium channel gamma-8 subunit

TARP gamma-8

calcium channel, voltage-dependent, gamma subunit 8

neuronal voltage-gated calcium channel gamma-8 subunit

transmembrane AMPAR regulatory protein gamma-8

Cacng8 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Cacng8 Q8VHW5 PPP3CA Homo sapiens Q08209
Pull Down
24418105
种属内
Cacng8 Q8VHW5 Ppp3ca Rattus norvegicus P63329
Anti Bait CoIP
24418105
种属内
Cacng8 Q8VHW5 Ppp3ca Rattus norvegicus P63329
IF
24418105
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01815 CACNG8 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cacng8 NCBI NCBI:59283
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