2. Gene
  3. Ppp3ca - protein phosphatase 3 catalytic subunit alpha Gene

Ppp3ca - protein phosphatase 3 catalytic subunit alpha Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Calna1

基因 ID: 24674 | 基因类型: protein coding

关于 Ppp3ca

功能概要

Enables Calmodulin binding activity and calmodulin-dependent protein Phosphatase activity. Involved in several processes, including cellular response to glucose stimulus; negative regulation of Insulin secretion; and response to amphetamine. Located in cytosol. Part of Calcineurin complex. Is active in synapse. Colocalizes with slit diaphragm. Biomarker of kidney disease. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 91. Orthologous to human PPP3CA (protein Phosphatase 3 catalytic subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Ppp3ca 基因产物(1)

mRNA Protein Name
NM_017041.2 NP_058737.1 protein phosphatase 3 catalytic subunit alpha
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium-dependent protein serine/threonine phosphatase activity IDA
IDA: 通过直接分析推断
12135494 RGD
enables calmodulin binding IDA
IDA: 通过直接分析推断
12135494 RGD
enables calmodulin-dependent protein phosphatase activity IDA
IDA: 通过直接分析推断
24018048 RGD
enables phosphoprotein phosphatase activity IDA
IDA: 通过直接分析推断
1322410 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
10593895 RGD
enables protein serine/threonine phosphatase activity IDA
IDA: 通过直接分析推断
12135494 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
12135494 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to glucose stimulus IMP
IMP: 通过突变表型推断
19965390 RGD
involved in negative regulation of insulin secretion IMP
IMP: 通过突变表型推断
19965390 RGD
involved in protein dephosphorylation IDA
IDA: 通过直接分析推断
1322410 RGD
involved in protein import into nucleus IDA
IDA: 通过直接分析推断
21273244 RGD
involved in response to amphetamine IEP
IEP: 通过表达模式推断
11954050 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of calcineurin complex IDA
IDA: 通过直接分析推断
12135494 RGD
located in slit diaphragm IDA
IDA: 通过直接分析推断
27009276 RGD
is active in synapse IDA
IDA: 通过直接分析推断
1313851 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein phosphatase 3 catalytic subunit alpha

serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform

CAM-PRP catalytic subunit

CNA alpha

Calcineurin subunit A alpha

calcineurin A alpha

protein phosphatase 3, catalytic subunit, alpha isozyme

protein phosphatase-2Ba

Ppp3ca 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Ppp3ca P63329 Cacna1c Rattus norvegicus P22002
Phosphatase Assay
19478199
种属内
Ppp3ca P63329 Cacna1c Rattus norvegicus P22002
CoIP
19478199
种属内
Ppp3ca P63329 Cacng8 Rattus norvegicus Q8VHW5
Anti Bait CoIP
24418105
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11023 PPP3CA Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ppp3ca NCBI NCBI:5530
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z