2. Gene
  3. MOSPD2 - motile sperm domain containing 2 Gene

MOSPD2 - motile sperm domain containing 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含活动精子域 2

种属: Homo sapiens

基因 ID: 158747 | 基因类型: protein coding

关于 MOSPD2

Cytogenetic location: Xp22.2 Genomic coordinates (GRCh38): X:14,873,421-14,922,327 (from NCBI)

This gene has 6 transcripts (splice variants) and 227 orthologues. Ubiquitous expression in thyroid (RPKM 8.4), brain (RPKM 7.3) and 25 other tissues.

功能概要

参与单核细胞趋化性的正调节和中性粒细胞趋化性的正调节。位于内质网和内质网-内体膜的接触部位。是质膜的组成部分。 [由基因组资源联盟提供，2022 年 4 月]

Involved in positive regulation of monocyte chemotaxis and positive regulation of neutrophil chemotaxis. Located in endoplasmic reticulum and endoplasmic reticulum-endosome membrane contact site. Is integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

MOSPD2 基因产物(3)

mRNA Protein Name
NM_001177475.2 NP_001170946.1 motile sperm domain-containing protein 2 isoform 2
NM_001330241.2 NP_001317170.1 motile sperm domain-containing protein 2 isoform 3
NM_152581.4 NP_689794.1 motile sperm domain-containing protein 2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables FFAT motif binding IDA
IDA: 通过直接分析推断
33124732 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
29858488 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in lipid droplet formation IDA
IDA: 通过直接分析推断
35389430 GOA
involved in positive regulation of monocyte chemotaxis IDA
IDA: 通过直接分析推断
28137892 GOA
involved in positive regulation of neutrophil chemotaxis IDA
IDA: 通过直接分析推断
28137892 GOA
involved in protein homooligomerization IDA
IDA: 通过直接分析推断
33124732 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
29858488 GOA
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
35389430 GOA
located in endoplasmic reticulum-endosome membrane contact site IDA
IDA: 通过直接分析推断
29858488 GOA
located in organelle membrane contact site IDA
IDA: 通过直接分析推断
29858488 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
28137892 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MOSPD2 蛋白结构

CRAL_TRIO

CRAL_TRIO: CRAL/TRIO domain (93 - 234)

Motile_Sperm

Motile_Sperm: MSP (Major sperm protein) domain (328 - 430)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 518 a.a.
蛋白主名 其他名称

motile sperm domain-containing protein 2

MOSPD2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
MOSPD2 Q8NHP6 RMDN3 Homo sapiens Q96TC7
Anti Tag CoIP
29858488
种属内
MOSPD2 Q8NHP6 BTN1A1 Homo sapiens Q13410
Y2H Array
32296183
种属内
MOSPD2 Q8NHP6 BTN1A1 Homo sapiens Q13410
Y2H Prey Pooling
32296183
种属内
MOSPD2 Q8NHP6 OSBPL1A Homo sapiens Q9BXW6
Anti Tag CoIP
29858488
种属内
MOSPD2 Q8NHP6 STARD3 Homo sapiens Q14849
Anti Tag CoIP
29858488
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Fanconi Anemia, Complementation Group B

Fanconi Anemia Complementation Group B

FANCB

Facb

Fa2

Fanconi Pancytopenia Type 2

Fanconi Pancytopenia, Type 2
Fanconi Anemia, Complementation Group A

Fanconi Anemia

Fanconi Pancytopenia

Fanconi Anemia Complementation Group A

FANCA

Fa

Fanconi Panmyelopathy

Fanconi'S Anemia

Fanconi Anaemia

Fanconi'S Anaemia

Fanconi Hypoplastic Anemia

Estren-Dameshek Variant Of Fanconi Anemia

Estren-Dameshek Variant Of Fanconi Pancytopenia

Fanconi Anemia Estren-Dameshek Variant

Fanconis Anemia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08601 MOSPD2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus MOSPD2 VGNC VGNC:63566
Mus musculus MOSPD2 MGD MGI:1924013
Rattus norvegicus MOSPD2 RGD RGD:1563952
Macaca mulatta MOSPD2 VGNC VGNC:74847
Canis familiaris MOSPD2 VGNC VGNC:43325
Others MOSPD2 NCBI
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