MAGEB6 - MAGE family member B6 Gene

中文名称：MAGE 家族成员 B6

种属: Homo sapiens

同用名: CT3.4; MAGE-B6; MAGEB6A

关于 MAGEB6

功能概要

该基因是 MAGEB 基因家族的成员。该家族成员的整个编码序列位于最后一个外显子中，编码的蛋白质彼此之间具有 50% 至 68% 的序列同一性。 MAGEB 基因的启动子和第一个外显子显示出相当大的变异性，表明该基因家族的存在使得相同的功能能够在不同的转录控制下表达。该基因在睾丸和各种组织学类型的很大一部分肿瘤中表达。 MAGEB 基因聚集在染色体 Xp22-p21 上。[RefSeq 提供，2008 年 7 月]

This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each Other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is expressed in testis, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. [provided by RefSeq, Jul 2008]