1. Gene
  2. Ifngr1 - interferon gamma receptor 1 Gene

Ifngr1 - interferon gamma receptor 1 Gene

种属: Mus musculus

同用名: Ifgr; CD119; Ifngr; Nktar; IFN-gammaR

基因 ID: 15979 | 基因类型: protein coding

关于 Ifngr1

功能概要

Predicted to enable cytokine receptor activity. Involved in several processes, including astrocyte activation; negative regulation of amyloid-beta clearance; and positive regulation of macromolecule metabolic process. Acts upstream of or within defense response to virus. Predicted to be located in several cellular components, including dendrite; endoplasmic reticulum; and postsynaptic density. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system; cerebral cortex; cranium; female reproductive system; and liver. Used to study osteoporosis. Human ortholog(s) of this gene implicated in asthma; hepatitis B; immunodeficiency 27A; immunodeficiency 27B; and tuberculosis. Orthologous to human IFNGR1 (interferon gamma receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Ifngr1 基因产物(1)

mRNA Protein Name
NM_010511.3 NP_034641.1 interferon gamma receptor 1 precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in astrocyte activation IGI
IGI: 通过遗传相互作用推断
17255335 MGI
acts upstream of or within defense response to virus IMP
IMP: 通过突变表型推断
25268627 MGI
involved in microglial cell activation IGI
IGI: 通过遗传相互作用推断
17255335 MGI
involved in negative regulation of amyloid-beta clearance IGI
IGI: 通过遗传相互作用推断
17255335 MGI
involved in positive regulation of amyloid-beta formation IGI
IGI: 通过遗传相互作用推断
17255335 MGI
involved in positive regulation of gene expression IGI
IGI: 通过遗传相互作用推断
17255335 MGI
involved in positive regulation of tumor necrosis factor production IGI
IGI: 通过遗传相互作用推断
17255335 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

interferon gamma receptor 1

IFN-gamma receptor 1

IFN-gamma-R-alpha

IFN-gamma-R1

INF-g receptor

interferon gamma receptor alpha-chain

重组 Ifngr1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72611 IFN-gamma R1/CD119 Protein, Mouse (HEK293, His) P15261 (A26-D253) ≥95%
HY-P73133 IFN-gamma R1/CD119 Protein, Mouse (HEK293, Fc) P15261 (A26-D253) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ifngr1 NCBI NCBI:3459
Macaca fascicularis Ifngr1 NCBI NCBI:101866179
Rattus norvegicus Ifngr1 NCBI NCBI:116465