BRINP1 - BMP/retinoic acid inducible neural specific 1 Gene

中文名称：BMP/视黄酸诱导神经特异性 1

种属: Homo sapiens

同用名: DBC1; FAM5A; DBCCR1

基因 ID: 1620 | 基因类型: protein coding

关于 BRINP1

Cytogenetic location: 9q33.1 Genomic coordinates (GRCh38): 9:119,166,629-119,369,435 (from NCBI)

This gene has 3 transcripts (splice variants), 206 orthologues and 2 paralogues. Biased expression in brain (RPKM 23.7) and adrenal (RPKM 2.3).

功能概要

该基因位于在某些膀胱癌中显示杂合性缺失的染色体区域内。它包含一个 5' CpG 岛，可能是超甲基化的常见目标，并且它可能在某些膀胱癌中经历基于超甲基化的沉默。[RefSeq 提供，2008 年 7 月]

This gene is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers. It contains a 5' CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder cancers. [provided by RefSeq, Jul 2008]

BRINP1 基因产物(1)

mRNA	Protein	Name
NM_014618.3	NP_055433.2	BMP/retinoic acid-inducible neural-specific protein 1 precursor

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	12442002	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in negative regulation of cell cycle	IDA IDA: 通过直接分析推断	11420708	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in cytoplasm	IDA IDA: 通过直接分析推断	11420708	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

BRINP1 蛋白结构

MACPF

0
200
400
600
761 a.a.

蛋白主名

其他名称

BMP/retinoic acid-inducible neural-specific protein 1

bA574M5.1 (deleted in bladder cancer chromosome region candidate 1 (IB3089A))

BRINP1 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	BRINP1	O60477	ZNF326	Homo sapiens	Q5BKZ1	GMS	22446626

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Bladder Cancer

Urinary Bladder Cancer	Bladder Carcinoma
Urinary Bladder Carcinoma	Bladder Neoplasm
Bladder Tumor	Cancer, Bladder
Malignant Neoplasm Of Urinary Bladder	Carcinoma Of Bladder
Bladder Cancer, Somatic	Tumor Of The Bladder
Carcinoma Of Urinary Bladder	Bladder Carcinoma Urinary
Cancer Of The Urinary Bladder	Cancer, Urinary Bladder
Malignant Bladder Neoplasm	Malignant Bladder Tumor
Neoplasm Of The Bladder	Neoplasm Of The Urinary Bladder
Tumor Of The Urinary Bladder	Urinary Bladder Neoplasm
BLC	Urothelial Carcinoma Of The Bladder
Bladder Tumors	Urinary Bladder Neoplasms
Bladder Cancer Nos	Vesical Cancer Nos
Malignant Neoplasm Of Bladder, Part Unspecified	Malignant Tumour Of Urinary Bladder
Primary Malignant Neoplasm Of Bladder

Transitional Cell Carcinoma

Transitional Cell Neoplasm	Carcinoma, Transitional Cell
Transitional Carcinoma	Transitional Cell Tumor
Urothelial Cell Carcinoma	Carcinoma Transitional Cell
Transitional Cell Carcinoma Of Bladder

Gallbladder Sarcoma

Malignant Mesenchymal Tumor Of Gallbladder

Papillary Transitional Carcinoma

Papillary Transitional Cell Carcinoma

Non-Invasive Bladder Papillary Urothelial Neoplasm

Bladder Papillary Neoplasm Of Low Malignant Potential	Bladder Punlmp
Papillary Urothelial Neoplasm Of Low Malignant Potential	Papillary Transitional Cell Neoplasm Of Low Malignant Potential

Bladder Papillary Transitional Cell Neoplasm

Urinary Bladder Papillary Urothelial Neoplasm

Bladder Papillary Urothelial Neoplasm

Urinary Tract Papillary Transitional Cell Benign Neoplasm

Inverted Papilloma Of Urinary Tract	Papillary Transitional Cell Neoplasm Of The Urinary Tract
Urinary Tract Inverted Papilloma	Inverted Urothelial Papilloma

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS01620	BRINP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	BRINP1	RGD	RGD:708519
Macaca mulatta	BRINP1	VGNC	VGNC:104880
Felis catus	BRINP1	VGNC	VGNC:102903
Canis familiaris	BRINP1	VGNC	VGNC:38527
Mus musculus	BRINP1	MGD	MGI:1928478
Bos taurus	BRINP1	VGNC	VGNC:26567

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