2. Gene
  3. Lcn2 - lipocalin 2 Gene

Lcn2 - lipocalin 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: NRL; 24p3; Sip24

基因 ID: 16819 | 基因类型: protein coding

关于 Lcn2

功能概要

Enables iron ion binding activity. Involved in innate immune response; positive regulation of cold-induced thermogenesis; and siderophore transport. Acts upstream of or within extrinsic apoptotic signaling pathway in absence of ligand; response to bacterium; and response to virus. Located in extracellular space. Is expressed in several structures, including genitourinary system; gut; liver; lung; and spleen. Human ortholog(s) of this gene implicated in intrahepatic cholangiocarcinoma and urinary tract Infection. Orthologous to human LCN2 (lipocalin 2). [provided by Alliance of Genome Resources, Apr 2022]

Lcn2 基因产物(1)

mRNA Protein Name
NM_008491.1 NP_032517.1 neutrophil gelatinase-associated lipocalin precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables iron ion binding IDA
IDA: 通过直接分析推断
16377569 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
16377569 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within extrinsic apoptotic signaling pathway in absence of ligand IDA
IDA: 通过直接分析推断
16377569 MGI
involved in innate immune response IMP
IMP: 通过突变表型推断
16446425 MGI
involved in positive regulation of cold-induced thermogenesis IMP
IMP: 通过突变表型推断
20332347 MGI
acts upstream of or within response to bacterium IEP
IEP: 通过表达模式推断
23012479 MGI
acts upstream of or within response to virus IDA
IDA: 通过直接分析推断
2542864 MGI
involved in siderophore transport IDA
IDA: 通过直接分析推断
16377569 MGI
involved in siderophore transport IMP
IMP: 通过突变表型推断
20550936 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular region IDA
IDA: 通过直接分析推断
16377569 MGI
located in extracellular space IDA
IDA: 通过直接分析推断
29402223 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neutrophil gelatinase-associated lipocalin

SV-40-induced 24P3 protein

neu-related lipocalin

oncogene 24p3

p25

secreted inducible protein 24

siderocalin LCN2

重组 Lcn2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70658 Lipocalin-2/NGAL Protein, Mouse (HEK293, His) P11672 (Q21-N200) ≥95%
HY-P78329 Lipocalin-2/NGAL Protein, Mouse (HEK293, Fc) P11672 (Q21-N200) ≥95%
HY-P70658A Lipocalin-2/NGAL Protein, Mouse (HEK293, C-His) P11672 (Q21-N200) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-Q45780 ZINC00640089 99.82% 否
HY-148364 ZINC00784494 99.32% 否
HY-RS07557 LCN2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-132195 RORγt inverse agonist 14 Inhibitor / 否
HY-158049 Anticancer agent 199 Inducer / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lcn2 NCBI NCBI:3934
Macaca fascicularis Lcn2 NCBI NCBI:102137149
Rattus norvegicus Lcn2 NCBI NCBI:170496
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