2. Gene
  3. Lcn2 - lipocalin 2 Gene

Lcn2 - lipocalin 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Sip24

基因 ID: 170496 | 基因类型: protein coding

关于 Lcn2

功能概要

Enables enterobactin binding activity; identical protein binding activity; and Protease binding activity. Involved in several processes, including cellular response to cytokine stimulus; memory; and regulation of neuron apoptotic process. Located in cytosol and extracellular space. Used to study intrahepatic cholangiocarcinoma and retinal degeneration. Biomarker of several diseases, including acute kidney failure; congenital diaphragmatic hernia; obesity; pulmonary hypertension; and transient cerebral ischemia. Human ortholog(s) of this gene implicated in urinary tract Infection. Orthologous to human LCN2 (lipocalin 2). [provided by Alliance of Genome Resources, Apr 2022]

Lcn2 基因产物(1)

mRNA Protein Name
NM_130741.1 NP_570097.1 neutrophil gelatinase-associated lipocalin precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables enterobactin binding IPI
IPI: 通过物理相互作用推断
26004810 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
17148685 RGD
enables protease binding IPI
IPI: 通过物理相互作用推断
17148685 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in acute-phase response IEP
IEP: 通过表达模式推断
22249220 RGD
involved in cellular response to X-ray IEP
IEP: 通过表达模式推断
23331620 RGD
involved in cellular response to amyloid-beta IEP
IEP: 通过表达模式推断
24853299 RGD
involved in cellular response to hydrogen peroxide IDA
IDA: 通过直接分析推断
19129400 RGD
involved in cellular response to hypoxia IEP
IEP: 通过表达模式推断
24916903 RGD
involved in cellular response to increased oxygen levels IEP
IEP: 通过表达模式推断
24916903 RGD
involved in cellular response to interleukin-1 IEP
IEP: 通过表达模式推断
19329498 RGD
involved in cellular response to interleukin-6 IEP
IEP: 通过表达模式推断
22249220 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
19329498 RGD
involved in cellular response to nerve growth factor stimulus IEP
IEP: 通过表达模式推断
25412834 RGD
involved in cellular response to nutrient levels IEP
IEP: 通过表达模式推断
17356516 RGD
involved in cellular response to tumor necrosis factor IEP
IEP: 通过表达模式推断
19329498 RGD
involved in long-term memory IMP
IMP: 通过突变表型推断
32174475 RGD
involved in negative regulation of hippocampal neuron apoptotic process IMP
IMP: 通过突变表型推断
32174475 RGD
involved in positive regulation of apoptotic process IGI
IGI: 通过遗传相互作用推断
26013918 RGD
involved in positive regulation of cell projection organization IDA
IDA: 通过直接分析推断
19129400 RGD
involved in positive regulation of endothelial cell migration IDA
IDA: 通过直接分析推断
25557118 RGD
involved in positive regulation of endothelial tube morphogenesis IDA
IDA: 通过直接分析推断
25557118 RGD
involved in positive regulation of gene expression IDA
IDA: 通过直接分析推断
19860839 RGD
involved in positive regulation of hippocampal neuron apoptotic process IDA
IDA: 通过直接分析推断
26004810 RGD
involved in positive regulation of iron ion import across plasma membrane IDA
IDA: 通过直接分析推断
25557118 RGD
involved in positive regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
30574656 RGD
involved in positive regulation of reactive oxygen species biosynthetic process IDA
IDA: 通过直接分析推断
25557118 RGD
involved in positive regulation of reactive oxygen species metabolic process IMP
IMP: 通过突变表型推断
30574656 RGD
involved in response to bacterium IEP
IEP: 通过表达模式推断
19303090 RGD
involved in response to blue light IEP
IEP: 通过表达模式推断
30574656 RGD
involved in response to fructose IEP
IEP: 通过表达模式推断
24587658 RGD
involved in response to herbicide IDA
IDA: 通过直接分析推断
19129400 RGD
involved in response to iron(II) ion IEP
IEP: 通过表达模式推断
23416150 RGD
involved in response to kainic acid IEP
IEP: 通过表达模式推断
26004810 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
26004810 RGD
involved in response to mycotoxin IEP
IEP: 通过表达模式推断
18308701 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
19221211 RGD
involved in response to oxidative stress IEP
IEP: 通过表达模式推断
17553663 RGD
involved in response to toxic substance IEP
IEP: 通过表达模式推断
22366155 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
20043115 RGD
involved in response to xenobiotic stimulus IMP
IMP: 通过突变表型推断
19860839 RGD
involved in short-term memory IMP
IMP: 通过突变表型推断
32174475 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
20057160 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neutrophil gelatinase-associated lipocalin

NGAL

alpha-2-microglobulin-related protein

alpha-2U globulin-related protein

lipocalin 2 (oncogene 24p3)

lipocalin 24p3

p25

siderocalin LCN2

重组 Lcn2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74774 Lipocalin-2/NGAL Protein, Rat (sf9, His) P30152 (Q21-N198) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-Q45780 ZINC00640089 99.82% 否
HY-148364 ZINC00784494 99.32% 否
HY-RS07557 LCN2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-132195 RORγt inverse agonist 14 Inhibitor / 否
HY-158049 Anticancer agent 199 Inducer / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lcn2 NCBI NCBI:3934
Macaca fascicularis Lcn2 NCBI NCBI:102137149
Mus musculus Lcn2 NCBI NCBI:16819
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