1. Gene
  2. ZNF467 - zinc finger protein 467 Gene

ZNF467 - zinc finger protein 467 Gene

中文名称:锌指蛋白 467

种属: Homo sapiens

同用名: EZI; Zfp467

基因 ID: 168544 | 基因类型: protein coding

关于 ZNF467

Cytogenetic location: 7q36.1 Genomic coordinates (GRCh38): 7:149,764,182-149,776,530 (from NCBI)

This gene has 2 transcripts (splice variants), 90 orthologues and 51 paralogues. Ubiquitous expression in spleen (RPKM 2.9), kidney (RPKM 2.5) and 25 other tissues.

功能概要

该基因编码的蛋白质是一种锌指蛋白,其在人类中的功能尚未阐明。然而,该蛋白质的小鼠直系同源物可增强脂肪细胞分化并抑制骨髓中的成骨细胞分化。小鼠蛋白也是几种基因的转录因子,可以帮助募集组蛋白脱乙酰酶复合物。[RefSeq 提供,2016 年 8 月]

The protein encoded by this gene is a zinc finger protein whose function has not yet been elucidated in humans. However, the mouse ortholog of this protein enhances adipocyte differentiation and suppresses osteoblast differentiation in bone marrow. The mouse protein also is a transcription factor for several genes and can help recruit histone deacetylase complexes. [provided by RefSeq, Aug 2016]

ZNF467 基因产物(2)

mRNA Protein Name
NM_001329856.2 NP_001316785.1 zinc finger protein 467 isoform 2
NM_207336.3 NP_997219.1 zinc finger protein 467 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

ZNF467 蛋白结构

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (175 - 198)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (206 - 226)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (230 - 254)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (261 - 282)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (286 - 311)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (355 - 377)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (445 - 469)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (487 - 509)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (529 - 554)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 595 a.a.
蛋白主名 其他名称

zinc finger protein 467

zinc finger protein EZI

ZNF467 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra ZNF467 Q7Z7K2 TLE5 Homo sapiens Q08117-2
Y2H Prey Pooling
32296183
Intra ZNF467 Q7Z7K2 TLE5 Homo sapiens Q08117-2
Y2H Array
32296183
Intra ZNF467 Q7Z7K2 KRTAP12-3 Homo sapiens P60328
Y2H Array
32296183
Intra ZNF467 Q7Z7K2 KRTAP12-3 Homo sapiens P60328
Y2H Prey Pooling
32296183
Intra ZNF467 Q7Z7K2 L3MBTL2 Homo sapiens Q969R5
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Bos taurus ZNF467 VGNC VGNC:37281
Rattus norvegicus ZNF467 RGD RGD:1561603
Canis familiaris ZNF467 VGNC VGNC:48735
Mus musculus ZNF467 MGD MGI:1916160
Felis catus ZNF467 VGNC VGNC:80763