1. Gene
  2. Sstr3 - somatostatin receptor 3 Gene

Sstr3 - somatostatin receptor 3 Gene

中文名称:生长抑素受体 3

种属: Rattus norvegicus

同用名: SSTR; Smstr28

基因 ID: 171044 | 基因类型: protein coding

关于 Sstr3

Primary_assembly 7: 110,092,575-110,099,769 reverse strand.mRatBN7.2:CM026980.1

This gene has 1 transcript (splice variant), 251 orthologues, 14 paralogues and is associated with 5 phenotypes. Biased expression in Brain (RPKM 43.2), Thymus (RPKM 37.4) and 4 other tissues.

功能概要

预计该基因编码的蛋白可启动 G 蛋白偶联受体活性;神经肽结合活性;和信号受体结合活性。参与多个过程,包括大脑发育;细胞对脂质的反应;和精子发生。位于细胞质和质膜中。与人类 SSTR3(生长抑素受体 3)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable G protein-coupled receptor activity; neuropeptide binding activity; and signaling receptor binding activity. Involved in several processes, including brain development; cellular response to lipid; and spermatogenesis. Located in cytoplasm and plasma membrane. Orthologous to human SSTR3 (Somatostatin Receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Sstr3 基因产物(1)

mRNA Protein Name
NM_133522.2 NP_598206.1 somatostatin receptor type 3
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to estradiol stimulus IEP
IEP: 通过表达模式推断
9564833 RGD
involved in cellular response to glucocorticoid stimulus IEP
IEP: 通过表达模式推断
14512709 RGD
involved in cerebellum development IEP
IEP: 通过表达模式推断
9166718 RGD
involved in forebrain development IEP
IEP: 通过表达模式推断
10805921 RGD
involved in response to starvation IEP
IEP: 通过表达模式推断
7956902 RGD
involved in spermatogenesis IEP
IEP: 通过表达模式推断
9421433 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Sstr3 蛋白结构

7tm_GPCRs

7tm_GPCRs: cl28897 (45 - 332)

7tm_GPCRs

7tm_GPCRs: cd14964 (47 - 71)

7tm_GPCRs

7tm_GPCRs: cd14964 (80 - 101)

7tm_GPCRs

7tm_GPCRs: cd14964 (117 - 139)

7tm_GPCRs

7tm_GPCRs: cd14964 (162 - 178)

7tm_GPCRs

7tm_GPCRs: cd14964 (204 - 227)

7tm_GPCRs

7tm_GPCRs: cd14964 (264 - 286)

7tm_GPCRs

7tm_GPCRs: cd14964 (300 - 325)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 428 a.a.
蛋白主名 其他名称

somatostatin receptor type 3

SS-3-R

SS3-R

SS3R

SSR-28

somatostatin receptor 28

somatostatin receptor subtype 3

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sstr3 NCBI NCBI:6753