2. Gene
  3. Mpo - myeloperoxidase Gene

Mpo - myeloperoxidase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: mKIAA4033

基因 ID: 17523 | 基因类型: protein coding

关于 Mpo

功能概要

Enables peroxidase activity. Acts upstream of or within several processes, including hypochlorous acid biosynthetic process; removal of superoxide radicals; and response to fungus. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; integumental system; and skeleton. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease 1; cystic fibrosis; kidney failure (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human MPO (myeloperoxidase). [provided by Alliance of Genome Resources, Apr 2022]

Mpo 基因产物(1)

mRNA Protein Name
NM_010824.2 NP_034954.2 myeloperoxidase precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables peroxidase activity IDA
IDA: 通过直接分析推断
10085024 MGI
enables peroxidase activity IMP
IMP: 通过突变表型推断
10085024 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
NOT acts upstream of or within defense response to Gram-positive bacterium IMP
IMP: 通过突变表型推断
10085024 MGI
acts upstream of or within defense response to fungus IMP
IMP: 通过突变表型推断
10085024 MGI
acts upstream of or within hydrogen peroxide catabolic process IDA
IDA: 通过直接分析推断
10085024 MGI
acts upstream of or within hydrogen peroxide catabolic process IMP
IMP: 通过突变表型推断
10085024 MGI
acts upstream of or within hypochlorous acid biosynthetic process IMP
IMP: 通过突变表型推断
10085024 MGI
acts upstream of or within removal of superoxide radicals IMP
IMP: 通过突变表型推断
10085024 MGI
acts upstream of or within respiratory burst involved in defense response IMP
IMP: 通过突变表型推断
10085024 MGI
acts upstream of or within response to yeast IMP
IMP: 通过突变表型推断
10085024 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

myeloperoxidase

重组 Mpo 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70282 Myeloperoxidase/MPO Protein, Mouse (HEK293, His) P11247 (M16-T718) ≥95%

相关产品

Clinical Phase
生物活性分子 (4)
目录号 产品名 作用方式
纯度 Phase
HY-17646 Verdiperstat Inhibitor 99.85% Phase 3
HY-145581 Mitiperstat 99.12% Phase 3
HY-106228 HLF1-11 Inhibitor 99.91% Phase 2
HY-105017 Evodenoson Agonist 99.74% Phase 2
Pre-clinical Phase
生物活性分子 (27)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-111341 AZD5904 Inhibitor 99.93% 否
HY-100873 PF-1355 Inhibitor 99.80% 否
HY-W002004 4-Amino-tempo 99.60% 否
HY-B0880 4-Aminobenzohydrazide Inhibitor 99.96% 否
HY-115486 MPO-IN-28 Inhibitor 99.28% 否
HY-N6937 (R,R)-Secoisolariciresinol diglucoside 99.84% 否
HY-125039 N-Acetyl lysyltyrosylcysteine amide Inhibitor 99.81% 否
HY-125859A Myeloperoxidase, human white blood cells Inhibitor / 否
HY-139915 MPO-IN-1 Inhibitor 99.02% 否
HY-145197 MPO-IN-3 Inhibitor 99.73% 否
HY-115828 APA-APA-MPO dihydrochloride / 否
HY-115829 APA-H-MPO hydrochloride / 否
HY-146651 MPO-IN-4 Inhibitor / 否
HY-147691 MPO-IN-5 Inhibitor / 否
HY-147692 COX-2-IN-14 Inhibitor / 否
HY-163332 MPO-IN-6 Inhibitor / 否
HY-163335 MPO-IN-7 Inhibitor / 否
HY-168002 MPO-IN-8 / 否
HY-N10439 3β-Acetoxy-hop-22(29)-ene Inhibitor / 否
HY-N11552 Sorbifolin Inhibitor / 否
HY-N6937S1 (R,R)-Secoisolariciresinol diglucoside-d6 / 否
HY-P10868 Pegtarazimod Inducer / 否
HY-RS08621 MPO Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-103388 NCX 466 Inhibitor / 否
HY-116188 HX1 / 否
HY-132132 Neutrophil elastase inhibitor 3 Inhibitor / 否
HY-138110 Toladryl Antagonist / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990812 Anti-Mouse myeloperoxidase/MPO Antibody (6D1) Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mpo NCBI NCBI:4353
Macaca fascicularis Mpo NCBI NCBI:102130410
Rattus norvegicus Mpo NCBI NCBI:303413
Macaca mulatta Mpo NCBI NCBI:714246
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