2. Gene
  3. Pirb - paired Ig-like receptor B Gene

Pirb - paired Ig-like receptor B Gene

  • 基因
  • 蛋白

种属: Mus musculus

同用名: Gp91; LIR-3; PIR-B; Lilrb3

基因 ID: 18733 | 基因类型: protein coding

关于 Pirb

功能概要

Enables amyloid-beta binding activity and protein homodimerization activity. Involved in learning or memory; regulation of protein metabolic process; and regulation of synaptic plasticity. Acts upstream of or within several processes, including B cell homeostasis; B cell mediated immunity; and myeloid dendritic cell differentiation. Predicted to be located in cytoplasm; external side of plasma membrane; and extracellular space. Predicted to be integral component of plasma membrane. Predicted to be active in plasma membrane. Is expressed in cerebral cortex; cerebral cortex subventricular zone; cerebral cortex ventricular layer; and ganglionic eminence. Orthologous to several human genes including LILRB5 (leukocyte immunoglobulin like receptor B5). [provided by Alliance of Genome Resources, Apr 2022]

Pirb 基因产物(2)

mRNA Protein Name
NM_001357394.1 NP_001344323.1 leukocyte immunoglobulin-like receptor subfamily B member 3 isoform 2 precursor
NM_011095.2 NP_035225.2 leukocyte immunoglobulin-like receptor subfamily B member 3 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables amyloid-beta binding IDA
IDA: 通过直接分析推断
24052308 MGI
enables amyloid-beta binding IMP
IMP: 通过突变表型推断
24052308 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
22660330 MGI
enables protein homodimerization activity IPI
IPI: 通过物理相互作用推断
24052308 MGI
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
24052308 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within B cell homeostasis IMP
IMP: 通过突变表型推断
12021780 MGI
acts upstream of or within B cell mediated immunity IMP
IMP: 通过突变表型推断
12021780 MGI
acts upstream of or within cytokine-mediated signaling pathway IMP
IMP: 通过突变表型推断
12021780 MGI
involved in learning or memory IGI
IGI: 通过遗传相互作用推断
24052308 MGI
acts upstream of or within myeloid dendritic cell differentiation IMP
IMP: 通过突变表型推断
12021780 MGI
involved in negative regulation of protein metabolic process IGI
IGI: 通过遗传相互作用推断
24052308 MGI
involved in positive regulation of long-term synaptic depression IGI
IGI: 通过遗传相互作用推断
24052308 MGI
involved in regulation of long-term synaptic potentiation IGI
IGI: 通过遗传相互作用推断
24052308 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

leukocyte immunoglobulin-like receptor subfamily B member 3

cell-surface glycoprotein p91

leukocyte immunoglobulin-like receptor 3

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3

paired immunoglobulin-like receptor B

重组 Pirb 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77064 LILRB3/CD85a Protein, Mouse (HEK293, His) AAC53219 (S25-Y640) ≥95%
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