1. Gene
  2. Ptgds - prostaglandin D2 synthase (brain) Gene

Ptgds - prostaglandin D2 synthase (brain) Gene

种属: Mus musculus

同用名: PGD2; PGDS; 21kDa; PGDS2; Ptgs3; L-PGDS

基因 ID: 19215 | 基因类型: protein coding

关于 Ptgds

功能概要

Enables prostaglandin-D synthase activity and retinoid binding activity. Involved in prostaglandin biosynthetic process and regulation of circadian sleep/wake cycle, sleep. Acts upstream of or within negative regulation of male germ cell proliferation. Located in extracellular region. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in carotid artery disease. Orthologous to human PTGDS (prostaglandin D2 synthase). [provided by Alliance of Genome Resources, Apr 2022]

Ptgds 基因产物(1)

mRNA Protein Name
NM_008963.3 NP_032989.2 prostaglandin-H2 D-isomerase precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables prostaglandin-D synthase activity IDA
IDA: 通过直接分析推断
17715133 MGI
enables retinoid binding IDA
IDA: 通过直接分析推断
17715133 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in gene expression IDA
IDA: 通过直接分析推断
26025376 MGI
involved in gene expression IMP
IMP: 通过突变表型推断
26025376 MGI
acts upstream of or within negative regulation of male germ cell proliferation IGI
IGI: 通过遗传相互作用推断
25142465 MGI
involved in prostaglandin biosynthetic process IDA
IDA: 通过直接分析推断
17715133 MGI
involved in regulation of circadian sleep/wake cycle, sleep IDA
IDA: 通过直接分析推断
10781097 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular region IDA
IDA: 通过直接分析推断
8922532 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

prostaglandin-H2 D-isomerase

PGD2 synthase

glutathione-independent PGD synthase

glutathione-independent PGD synthetase

lipocalin-type prostaglandin-D synthase

prostaglandin D2 synthase (21 kDa, brain)

prostaglandin-D2 synthase

重组 Ptgds 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73710 PGD2 Synthase/PTGDS Protein, Mouse (HEK293, His) NP_032989.2 (Q25-E189) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptgds NCBI NCBI:5730
Rattus norvegicus Ptgds NCBI NCBI:25526