1. Gene
  2. Ptgds - prostaglandin D2 synthase Gene

Ptgds - prostaglandin D2 synthase Gene

种属: Rattus norvegicus

同用名: PH2DISO

基因 ID: 25526 | 基因类型: protein coding

关于 Ptgds

功能概要

Enables prostaglandin-D synthase activity and retinoid binding activity. Involved in prostaglandin biosynthetic process and response to glucocorticoid. Located in Golgi apparatus and extracellular space. Biomarker of sensorineural hearing loss and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in carotid artery disease. Orthologous to human PTGDS (prostaglandin D2 synthase). [provided by Alliance of Genome Resources, Apr 2022]

Ptgds 基因产物(1)

mRNA Protein Name
NM_013015.2 NP_037147.1 prostaglandin-H2 D-isomerase precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables prostaglandin-D synthase activity IDA
IDA: 通过直接分析推断
7836410 RGD
enables retinoid binding IDA
IDA: 通过直接分析推断
9188476 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in prostaglandin biosynthetic process IDA
IDA: 通过直接分析推断
7836410 RGD
involved in response to glucocorticoid IEP
IEP: 通过表达模式推断
14618091 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
11058225 RGD
located in extracellular region IDA
IDA: 通过直接分析推断
8815894 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
17259069 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

prostaglandin-H2 D-isomerase

PGD2 synthase

PGDS

PGDS2

Prostaglandin D synthase

glutathione-independent PGD synthase

glutathione-independent PGD synthetase

lipocalin-type prostaglandin-D synthase

prostaglandin D2 synthase (brain)

重组 Ptgds 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73709 PGD2 Synthase/PTGDS Protein, Rat (HEK293, His) P22057/NP_037147.1 (Q25-E189) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptgds NCBI NCBI:5730
Mus musculus Ptgds NCBI NCBI:19215