1. Gene
  2. Rtkn - rhotekin Gene

Rtkn - rhotekin Gene

种属: Mus musculus

基因 ID: 20166 | 基因类型: protein coding

关于 Rtkn

功能概要

Enables GTPase inhibitor activity and small GTPase binding activity. Predicted to be involved in several processes, including Rho protein signal transduction; cytoskeleton-dependent cytokinesis; and septin ring organization. Predicted to act upstream of or within apoptotic process. Predicted to be located in cytosol. Predicted to be active in actomyosin contractile ring. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; liver and biliary system; and reproductive system. Orthologous to human RTKN (rhotekin). [provided by Alliance of Genome Resources, Apr 2022]

Rtkn 基因产物(10)

mRNA Protein Name
NM_001136227.2 NP_001129699.1 rhotekin isoform a
NM_001355524.2 NP_001342453.2 rhotekin isoform c
NM_001355525.2 NP_001342454.2 rhotekin isoform d
NM_001410312.1 NP_001397241.1 rhotekin isoform e
NM_001410313.1 NP_001397242.1 rhotekin isoform e
NM_001410314.1 NP_001397243.1 rhotekin isoform f
NM_001410315.1 NP_001397244.1 rhotekin isoform g
NM_001410316.1 NP_001397245.1 rhotekin isoform h
NM_009106.3 NP_033132.2 rhotekin isoform b
NM_133641.3 NP_598396.2 rhotekin isoform b
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GTPase inhibitor activity IDA
IDA: 通过直接分析推断
8662891 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
18448676 MGI
enables small GTPase binding IDA
IDA: 通过直接分析推断
8662891 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

rhotekin

Rtkn 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Rtkn Q8C6B2 RHOA Homo sapiens P61586 20300064
种属间
Rtkn Q8C6B2 RHOA Homo sapiens P61586 22404908
种属间
Rtkn Q8C6B2 RHOA Homo sapiens P61586 20348415
种属内
Rtkn Q8C6B2 Rhoa Mus musculus Q9QUI0 20348415
种属内
Rtkn Q8C6B2 Rhoa Mus musculus Q9QUI0 18448676
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rtkn NCBI NCBI:6242