1. Gene
  2. Ccl11 - chemokine (C-C motif) ligand 11 Gene

Ccl11 - chemokine (C-C motif) ligand 11 Gene

种属: Mus musculus

同用名: Scya11; eotaxin

基因 ID: 20292 | 基因类型: protein coding

关于 Ccl11

功能概要

Predicted to enable CCR3 Chemokine Receptor binding activity; chemokine activity; and protein dimerization activity. Involved in several processes, including modulation of age-related behavioral decline; negative regulation of neurogenesis; and positive regulation of angiogenesis. Acts upstream of or within branching involved in mammary gland duct morphogenesis and mammary duct terminal end bud growth. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in embryo; endocardial lining; liver parenchyma; liver vasculature; and yolk sac blood vessel. Human ortholog(s) of this gene implicated in asthma; human immunodeficiency virus infectious disease; hyperglycemia; and multiple sclerosis. Orthologous to several human genes including CCL11 (C-C motif chemokine ligand 11). [provided by Alliance of Genome Resources, Apr 2022]

Ccl11 基因产物(1)

mRNA Protein Name
NM_011330.3 NP_035460.1 eotaxin precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within branching involved in mammary gland duct morphogenesis IMP
IMP: 通过突变表型推断
10804170 MGI
involved in learning or memory IDA
IDA: 通过直接分析推断
21886162 MGI
acts upstream of or within mammary duct terminal end bud growth IMP
IMP: 通过突变表型推断
10804170 MGI
involved in negative regulation of neurogenesis IDA
IDA: 通过直接分析推断
21886162 MGI
involved in positive regulation of angiogenesis IMP
IMP: 通过突变表型推断
19525930 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

eotaxin

C-C motif chemokine 11

eosinophil chemotactic protein

small chemokine (C-C motif) ligand 11

small-inducible cytokine A11

重组 Ccl11 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7160 Eotaxin/CCL11 Protein, Mouse P48298 (H24-P97) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ccl11 NCBI NCBI:6356
Rattus norvegicus Ccl11 NCBI NCBI:29397
Macaca mulatta Ccl11 NCBI NCBI:574218