2. Gene
  3. Ccl11 - C-C motif chemokine ligand 11 Gene

Ccl11 - C-C motif chemokine ligand 11 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Scya11

基因 ID: 29397 | 基因类型: protein coding

关于 Ccl11

功能概要

Enables chemokine activity. Involved in several processes, including ERK1 and ERK2 cascade; leukocyte chemotaxis; and response to interleukin-13. Located in extracellular space. Used to study allergic rhinitis; asthma; pleurisy; and pneumonia. Biomarker of several diseases, including allergic conjunctivitis; pneumonia; prostatitis; rhinitis; and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in asthma; human immunodeficiency virus infectious disease; hyperglycemia; and multiple sclerosis. Orthologous to several human genes including CCL11 (C-C motif chemokine ligand 11). [provided by Alliance of Genome Resources, Apr 2022]

Ccl11 基因产物(1)

mRNA Protein Name
NM_019205.2 NP_062078.1 eotaxin precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chemokine activity IDA
IDA: 通过直接分析推断
9458816 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in ERK1 and ERK2 cascade IGI
IGI: 通过遗传相互作用推断
12413953 RGD
involved in actin filament organization IDA
IDA: 通过直接分析推断
12413953 RGD
involved in chronic inflammatory response IEP
IEP: 通过表达模式推断
10861753 RGD
involved in eosinophil chemotaxis IDA
IDA: 通过直接分析推断
9458816 RGD
involved in eosinophil chemotaxis IMP
IMP: 通过突变表型推断
9531320 RGD
involved in mast cell chemotaxis IDA
IDA: 通过直接分析推断
12413953 RGD
involved in response to interleukin-13 IEP
IEP: 通过表达模式推断
15953562 RGD
involved in response to interleukin-4 IEP
IEP: 通过表达模式推断
11071660 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
9458816 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

eotaxin

C-C motif chemokine 11

chemokine (C-C motif) ligand 11

eosinophil chemotactic protein

small inducible cytokine subfamily A11

small-inducible cytokine A11

重组 Ccl11 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71901 CCL11 Protein, Rat P97545 (H24-P97) ≥95%

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P99474 Bertilimumab Inhibitor / Phase 2
Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N2609 7,4'-Dihydroxyflavone Inhibitor 99.68% 否
HY-103361 SB297006 Antagonist 99.88% 否
HY-110295 SPL-334 Inhibitor / 否
HY-RS02081 CCL11 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-111198 YM-355179 fumarate / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ccl11 NCBI NCBI:6356
Mus musculus Ccl11 NCBI NCBI:20292
Macaca mulatta Ccl11 NCBI NCBI:574218
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