1. Gene
  2. Sstr3 - somatostatin receptor 3 Gene

Sstr3 - somatostatin receptor 3 Gene

中文名称:生长抑素受体 3

种属: Mus musculus

同用名: sst3; Smstr3; Smstr-3

基因 ID: 20607 | 基因类型: protein coding

关于 Sstr3

Chromosome 15: 78,421,208-78,428,885 reverse strand.GRCm39:CM001008.3

This gene has 2 transcripts (splice variants), 251 orthologues and 15 paralogues. Biased expression in frontal lobe adult (RPKM 2.7), cortex adult (RPKM 2.1) and 9 other tissues.

功能概要

该基因编码的蛋白可启动信号受体结合活性。预计参与神经肽信号通路。预测作用于 G 蛋白偶联受体信号通路的上游或内部。位于纤毛膜和非运动纤毛中。以多种结构表达,包括肾上腺;脑;胆囊;泌尿生殖系统;和直觉。与人类 SSTR3(生长抑素受体 3)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables signaling receptor binding activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Located in ciliary membrane and non-motile cilium. Is expressed in several structures, including adrenal gland; brain; gallbladder; genitourinary system; and gut. Orthologous to human SSTR3 (Somatostatin Receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Sstr3 基因产物(3)

mRNA Protein Name
NM_009218.3 NP_033244.2 somatostatin receptor type 3
NM_001411768.1 NP_001398697.1 somatostatin receptor type 3
NM_001356961.1 NP_001343890.1 somatostatin receptor type 3
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
23029470 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in ciliary membrane IDA
IDA: 通过直接分析推断
22179047 MGI
located in cilium IDA
IDA: 通过直接分析推断
22718903 MGI
located in neuron projection IDA
IDA: 通过直接分析推断
23029470 MGI
located in non-motile cilium IDA
IDA: 通过直接分析推断
18334641 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
23029470 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Sstr3 蛋白结构

7tm_GPCRs

7tm_GPCRs: cl28897 (45 - 332)

7tm_GPCRs

7tm_GPCRs: cd14964 (47 - 71)

7tm_GPCRs

7tm_GPCRs: cd14964 (80 - 101)

7tm_GPCRs

7tm_GPCRs: cd14964 (117 - 139)

7tm_GPCRs

7tm_GPCRs: cd14964 (162 - 178)

7tm_GPCRs

7tm_GPCRs: cd14964 (204 - 227)

7tm_GPCRs

7tm_GPCRs: cd14964 (264 - 286)

7tm_GPCRs

7tm_GPCRs: cd14964 (300 - 325)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 428 a.a.
蛋白主名 其他名称

somatostatin receptor type 3

SS-3-R

SS3-R

SS3R

SSR-28

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sstr3 NCBI NCBI:6753