Plk2 - polo like kinase 2 Gene

中文名称：马球样激酶 2

种属: Mus musculus

同用名: Snk

关于 Plk2

功能概要

该基因编码的蛋白可启动蛋白质丝氨酸/苏氨酸激酶活性。参与多个过程，包括对骨髓细胞凋亡过程的负调控；细胞衰老的负调节；和参与发芽血管生成的细胞迁移的正调节。作用于有丝分裂细胞周期的上游或内部，并对凋亡过程进行负调节。位于染色质中。以多种结构表达，包括消化系统；后肢指间区；外皮系统；神经系统;和骨架。与人类 PLK2（马球样激酶 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables protein serine/threonine kinase activity. Involved in several processes, including negative regulation of apoptotic process in bone marrow cell; negative regulation of cellular senescence; and positive regulation of cell migration involved in sprouting angiogenesis. Acts upstream of or within mitotic cell cycle and negative regulation of apoptotic process. Located in chromatin. Is expressed in several structures, including alimentary system; hindlimb interdigital region; integumental system; nervous system; and skeleton. Orthologous to human PLK2 (polo like kinase 2). [provided by Alliance of Genome Resources, Apr 2022]