2. Gene
  3. Tead4 - TEA domain family member 4 Gene

Tead4 - TEA domain family member 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Tef3; Tefr; Etfr2; FR-19; Rtef1; TEF-3; Tefr1; ETFR-2; TEAD-4; Tefr1a; Tcf13r1

基因 ID: 21679 | 基因类型: protein coding

关于 Tead4

功能概要

This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. This factor may play a role in the embryonic development of skeletal muscle. Alternatively spliced transcripts encoding distinct isoforms, which are translated through the use of a non-AUG (AUU) initiation codon, have been described for this gene. [provided by RefSeq, Jul 2008]

Tead4 基因产物(2)

mRNA Protein Name
NM_001080979.1 NP_001074448.2 transcriptional enhancer factor TEF-3 isoform b
NM_011567.2 NP_035697.3 transcriptional enhancer factor TEF-3 isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
8702974 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
16207754 MGI
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
26902285 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
8702974 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
22632831 MGI
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
22529382 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within blastocyst formation IMP
IMP: 通过突变表型推断
18804437 MGI
acts upstream of or within cell fate commitment IDA
IDA: 通过直接分析推断
22529382 MGI
acts upstream of or within cell fate specification IMP
IMP: 通过突变表型推断
18083014 MGI
acts upstream of or within embryo implantation IMP
IMP: 通过突变表型推断
18083014 MGI
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
18083014 MGI
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
26902285 MGI
acts upstream of or within positive regulation of stem cell population maintenance IGI
IGI: 通过遗传相互作用推断
20516196 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
16207754 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
16207754 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
22529382 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
18083014 MGI
acts upstream of or within trophectodermal cell fate commitment IMP
IMP: 通过突变表型推断
18083014 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
22529382 MGI
part of protein-DNA complex IDA
IDA: 通过直接分析推断
22529382 MGI
part of transcription regulator complex IDA
IDA: 通过直接分析推断
16207754 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcriptional enhancer factor TEF-3

ETF-related factor-2

FGF-regulated 19

RTEF-1

TEF-1-related factor 1

TEF-1-related factor FR-19

重组 Tead4 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71575 ETFR-2/TEAD-4 Protein, Mouse Q62296-1 (R210-E427) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-125269 TED-347 Inhibitor 98.97% 否
HY-139330 MGH-CP1 Inducer 99.56% 否
HY-RS14345 TEAD4 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-160657 DC-TEADin04 / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tead4 NCBI NCBI:7004
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